Anti-MGLUR1 + MGLUR5 (Polyclonal), ALEXA Fluor 594

Anti-MGLUR1 + MGLUR5 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489

Size 100 microliters

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Type	Conjugated Primary Antibody
Conjugated with	594, ALEXA FLUOR®
Host organism	Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide	MGLUR1 + MGLUR5
Specificity	This antibody reacts specifically with MGLUR1 + MGLUR5
Modification	No modification has been applied to this antibody
Modification site	None
Clonality	Polyclonal Antibody
Clone	Polyclonal Antibodies
Concentration	1ug per 1ul
Subcellular locations	N/A
Antigen Source	KLH conjugated synthetic peptide derived from human MGLUR1 + MGLUR5
Gene ID	N/A
Swiss Prot	N/A
Applications	IF(IHC-P)
Applications with corresponding dilutions	IF(IHC-P)(1:50-200)
Cross reactive species	Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details	However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information	AMPA and kainite receptors that are involved in the fast excitatory synaptic transmission, For many years it had been considered to act only on the ligand-gated receptor channels-termed NMDA, Group-I receptors stimulate phospholipase C as revealed by an increase in phosphoinositide turnover and calcium release from internal stores, Group-II and -III receptors are coupled to the inhibition of adenylyl cyclase, In expression systems, Recently, The Group-I receptors include Metabotropic Glutamate Receptor 5 and Metabotropic Glutamate Receptor 1a, The Group-II receptors in include mGluR2 and mGluR3, These receptors are called metabotropic glutamate receptors, glutamate has been shown to regulate enzymes producing second messengers via specific receptors coupled to G-proteins, Glutamate is the main excitatory neurotransmitter in the brain
Purification method	Purified by Protein A
Storage	50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission	590nm/617nm
Synonyms	MGLUR5 GPRC1E mGlu5 PPP1R86
Also known as	MGLUR1 + MGLUR5 Polyclonal Antibody
Other name	Anti-MGLUR1 + MGLUR5 Polyclonal
Advisory	For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
Properties	For facs or microscopy Alexa 1 conjugate
Conjugation	Alexa Fluor
Group	Polyclonals and antibodies
About	The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene target	MGLUR1 + MGLUR5
Short name	Anti-MGLUR1 + MGLUR5 (Polyclonal) Fluor 594
Technique	Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different
Label	ALEXA
Alternative name	ALEXA Fluor 594, antibody to-MGLUR1 and MGLUR5 (polyclonal)
Alternative technique	polyclonals
Identity	4597
Gene	GRM5
Long gene name	glutamate metabotropic receptor 5
Synonyms gene name	glutamate receptor, metabotropic 5
Synonyms name	protein phosphatase 1, regulatory subunit 86
Locus	11q14, 2-q14, 3
Discovery year	1993-10-22
GenBank acession	D28538
Entrez gene record	2915
Pubmed identfication	7908515
RefSeq identity	NM_000842
Classification	Glutamate metabotropic receptors Protein phosphatase 1 regulatory subunits
Havana BLAST/BLAT	OTTHUMG00000134306

Anti-MGLUR1 + MGLUR5 (Polyclonal), ALEXA Fluor 594

Anti-MGLUR1 + MGLUR5 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

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