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Anti-Myosin VIIa (Polyclonal), ALEXA Fluor 594

Anti-Myosin VIIa (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideMyosin VIIa
SpecificityThis antibody reacts specifically with Myosin VIIa
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsCytoplasm
Antigen SourceKLH conjugated synthetic peptide derived from human Myosin VIIa
Gene ID4647
Swiss ProtQ13402
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive speciesHuman (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells, In the inner ear, In the retina, Involved in hair-cell vesicle trafficking of aminoglycosides, Motor protein that is a part of the functional network formed by USH1C, Plays an important role in the distribution and migration of retinal pigment epithelial (RPE) melanosomes and phagosomes, Required for normal hearing, Their highly divergent tails bind to membranous compartments, USH1G, Unconventional myosins serve in intracellular movements, and in the regulation of opsin transport in retinal photoreceptors, morphogenesis and organization of cochlear hair cell bundles, plays an important role in differentiation, plays an important role in the renewal of the outer photoreceptor disks, which are known to induce ototoxicity (By similarity), which are then moved relative to actin filaments, Myosins are actin-based motor molecules with ATPase activity
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms NSRD2 MYO7A
Also known asMyosin VIIa Polyclonal Antibody
Other nameAnti-Myosin VIIa Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetMyosin VIIa
Short nameAnti-Myosin VIIa (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-Myosin VIIa (polyclonal)
Alternative techniquepolyclonals
Identity 2784
Gene DFNA11
Long gene name myosin VIIA
Synonyms gene USH1B DFNB2
Synonyms gene name myosin VIIA (Usher syndrome 1B (autosomal recessive, severe))
Locus 11q13, 5
Discovery year 1992-06-08
GenBank acession U39226
Entrez gene record 4647
Pubmed identfication 8884266
RefSeq identity NM_000260
Classification Myosins, class VII A-kinase anchoring proteins Deafness associated genes FERM domain containing
Havana BLAST/BLAT OTTHUMG00000152822
Locus Specific Databases Hereditary Hearing Loss Homepage Mutations of the Myosin VIIa Gene CCHMC-BMI &, UC Hearing Loss Mutation Database

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