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Anti-NFKB (Polyclonal), ALEXA Fluor 594

Anti-NFKB (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideNFKB p100/p52
SpecificityThe immunoge used to produce this antibody has 83% sequence similarity with NFKB p105/ p50NFKB
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locations Nucleus, Cytoplasm
Antigen SourceKLH conjugated synthetic peptide derived from human NFKB p52
Gene ID4791
Swiss ProtQ00653
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Alternative splicing results in multiple transcript variants, Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, Dec 2013], The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function, The p100 full-length protein is co-translationally processed into a p52 active form, The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner, There is a pseudogene for this gene on chromosome 18, [provided by RefSeq, some of which may result in the formation of fusion proteins, This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB)
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms KBRAS1 kappaB-Ras1
Also known asNFKB Polyclonal Antibody
Other nameAnti-NFKB Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetNFKB
Short nameAnti-NFKB (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-NFKB (polyclonal)
Alternative techniquepolyclonals
Identity 17899
Gene NKIRAS1
Long gene name NFKB inhibitor interacting Ras like 1
Synonyms gene name NFKB inhibitor interacting Ras-like protein 1
Locus 3p24, 2
Discovery year 2004-03-31
GenBank acession AF229839
Entrez gene record 28512
Pubmed identfication 10657303
RefSeq identity NM_020345
Classification RAS type GTPase family
Havana BLAST/BLAT OTTHUMG00000155605

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