Name : Anti-OVOL2/ZNF339 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN7916827517
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | OVOL2/ZNF339 |
| Specificity | This antibody reacts specifically with OVOL2/ZNF339 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human OVOL2/ZNF339 |
| Gene ID | 58495 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Deletion of Ovol1 in mice leads to germ cell degeneration and defective sperm production in adult males, Drosophila melanogaster, Members of the Ovo family include Ovol1 and Ovol2, Ovol1 acts as a transcriptional repressor by interacting with key developmental signaling pathways such as Wnt and TGF-â, Ovol1 has also been shown to repress itself as well as Ovol2, Ovol1 represses c-Myc and Id2 genes and establishes a balance between proliferation and differentiation of progenitor cells, Specifically, mouse and human, which is thought to regulate neural development and vascular angiogenesis during embryogenesis, &circ, «, /BMP, The Ovo family of zinc-finger transcription factors encode evolutionarily conserved genes including those from Caenorhabditis elegans |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | bA504H3, 3 HOVO2 CHED |
| Also known as | OVOL2/ZNF339 Polyclonal Antibody |
| Other name | Anti-OVOL2/ZNF339 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | OVOL2/ZNF339 |
| Short name | Anti-OVOL2/ZNF339 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-ovo-like 2 (Drosophila)/ZNF339 (polyclonal) |
| Alternative technique | polyclonals |
| Alternative to gene target | DNA-templated and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0046872 and metal ion binding and molecular function this GO :0048557 and embryonic digestive tract morphogenesis and biological process this GO :0051726 and regulation of cell cycle and biological process this GO :0060214 and endocardium formation and biological process this GO :0060347 and heart trabecula formation and biological process this GO :0060716 and labyrinthine layer blood vessel development and biological process, OVOL2 and IDBG-56804 and ENSG00000125850 and 58495, OVOL2 and IDBG-638777 and ENSBTAG00000008410 and 532761, Ovol2 and IDBG-208455 and ENSMUSG00000037279 and 107586, metal ion binding, nuclei, this GO :0000981 and sequence-specific DNA binding RNA polymerase II transcription factor activity and molecular function this GO :0001525 and angiogenesis and biological process this GO :0001755 and neural crest cell migration and biological process this GO :0001842 and neural fold formation and biological process this GO :0001947 and heart looping and biological process this GO :0003677 and DNA binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0006357 and regulation of transcription from RNA polymerase II promoter and biological process this GO :0006366 and transcription from RNA polymerase II promoter and biological process this GO :0007507 and heart development and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0009953 and dorsal/ventral pattern formation and biological process this GO :0010719 and negative regulation of epithelial to mesenchymal transition and biological process this GO :0010837 and regulation of keratinocyte proliferation and biological process this GO :0010944 and negative regulation of transcription by competitive promoter binding and biological process this GO :0044212 and transcription regulatory region DNA binding and molecular function this GO :0045617 and negative regulation of keratinocyte differentiation and biological process this GO :0045746 and negative regulation of Notch signaling pathway and biological process this GO :0045892 and negative regulation of transcription, this GO :0000981: sequence-specific DNA binding RNA polymerase II transcription factor activity, this GO :0000981: sequence-specific DNA binding RNA polymerase II transcription factor activity and also this GO :0003677: DNA binding and also this GO :0044212: transcription regulatory region DNA binding and also this GO :0046872: metal ion binding, this GO :0003677: DNA binding, this GO :0044212: transcription regulatory region DNA binding, this GO :0046872: metal ion binding, ovo-like 2 (Drosophila) |
| Identity | 15804 |
| Gene | OVOL2 |
| Long gene name | ovo like zinc finger 2 |
| Synonyms gene | ZNF339 CHED1 |
| Synonyms gene name | zinc finger protein 339 ovo-like 2 (Drosophila) corneal endothelial dystrophy 1 (autosomal dominant) |
| Locus | 20p11, 23 |
| Discovery year | 2001-09-17 |
| GenBank acession | AK022284 |
| Entrez gene record | 58495 |
| RefSeq identity | NM_021220 |
| Classification | Zinc fingers C2H2-type |
| Havana BLAST/BLAT | OTTHUMG00000031960 |