Name : Anti-PARP16 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN6742113848
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | PARP16 |
| Specificity | This antibody reacts specifically with PARP16 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human PARP16 |
| Gene ID | 54956 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Expressed as three isoforms produced by alternative splicing, PARP proteins are implicated in a variety of diseases, PARP-16 contains one PARP catalytic domain, PARP-16 is a 322 amino acid poly (ADP-ribose) polymerase protein localized to the membrane, PARPs use NAD+ as a substrate to catalytically transfer ADP-ribose residues onto protein acceptors, The PARP (poly(ADP-ribose) polymerase) proteins comprise a superfamily of enzymes that functionally modify histones and other nuclear proteins, The presence of these chains alters the function of the target protein and promotes cell survival, a process that, including cancer, leads to the formation of poly(ADPribose) chains on the protein, neurodegenerative and inflammatory disorders, thereby preventing cell death, when repeated multiple times, Poly(ADP-ribosylation) is a method of DNA damage-dependent posttranslational modification that helps to rescue injured proliferating cells from cell death |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | FLJ20509 FLJ25281 pART15 |
| Also known as | PARP16 Polyclonal Antibody |
| Other name | Anti-PARP16 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | PARP16 |
| Short name | Anti-PARP16 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-PARP16 (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 26040 |
| Gene | PARP16 |
| Long gene name | poly(ADP-ribose) polymerase family member 16 |
| Synonyms gene | C15orf30 |
| Synonyms gene name | chromosome 15 open reading frame 30 |
| Locus | 15q22, 31 |
| Discovery year | 2004-07-05 |
| GenBank acession | AK000516 |
| Entrez gene record | 54956 |
| Pubmed identfication | 15273990 |
| RefSeq identity | NM_017851 |
| Classification | Poly(ADP-ribose) polymerases |
| Havana BLAST/BLAT | OTTHUMG00000133138 |