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Anti-PARP16 (Polyclonal), ALEXA Fluor 594

Anti-PARP16 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptidePARP16
SpecificityThis antibody reacts specifically with PARP16
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human PARP16
Gene ID54956
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Expressed as three isoforms produced by alternative splicing, PARP proteins are implicated in a variety of diseases, PARP-16 contains one PARP catalytic domain, PARP-16 is a 322 amino acid poly (ADP-ribose) polymerase protein localized to the membrane, PARPs use NAD+ as a substrate to catalytically transfer ADP-ribose residues onto protein acceptors, The PARP (poly(ADP-ribose) polymerase) proteins comprise a superfamily of enzymes that functionally modify histones and other nuclear proteins, The presence of these chains alters the function of the target protein and promotes cell survival, a process that, including cancer, leads to the formation of poly(ADPribose) chains on the protein, neurodegenerative and inflammatory disorders, thereby preventing cell death, when repeated multiple times, Poly(ADP-ribosylation) is a method of DNA damage-dependent posttranslational modification that helps to rescue injured proliferating cells from cell death
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms FLJ20509 FLJ25281 pART15
Also known asPARP16 Polyclonal Antibody
Other nameAnti-PARP16 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetPARP16
Short nameAnti-PARP16 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-PARP16 (polyclonal)
Alternative techniquepolyclonals
Identity 26040
Gene PARP16
Long gene name poly(ADP-ribose) polymerase family member 16
Synonyms gene C15orf30
Synonyms gene name chromosome 15 open reading frame 30
Locus 15q22, 31
Discovery year 2004-07-05
GenBank acession AK000516
Entrez gene record 54956
Pubmed identfication 15273990
RefSeq identity NM_017851
Classification Poly(ADP-ribose) polymerases
Havana BLAST/BLAT OTTHUMG00000133138

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