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Anti-PDC6I (Polyclonal), ALEXA Fluor 594

Anti-PDC6I (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptidePDC6I
SpecificityThis antibody reacts specifically with PDC6I
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human PDC6I
Gene ID10015
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information -I, Appears to be an adapter for a subset of ESCRT-III proteins, Binds to the phospholipid lysobisphosphatidic acid (LBPA) which is abundant in MVBs internal membranes, Can replace TSG101 it its role of supporting HIV-1 release, Involved in HIV-1 virus budding, May play a role in the regulation of both apoptosis and cell proliferation, Required for completion of cytokinesis, The ESCRT machinery also functions in topologically equivalent membrane fission events, The MVB pathway appears to require the sequential function of ESCRT-O, such as CHMP4, such as the terminal stages of cytokinesis and enveloped virus budding (HIV-1 and other lentiviruses), this function implies the interaction with CHMP4B, to function at distinct membranes, -II and -III complexes, Class E VPS protein involved in concentration and sorting of cargo proteins of the multivesicular body (MVB) for incorporation into intralumenal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms ALG 2 interacting protein 1, ALG-2-interacting protein 1, ALG2 interacting protein X, Alix, Apoptosis linked gene 2 interacting protein X, DRIP4, Dopamine receptor interacting protein 4, HP95, KIAA1375, MGC17003, PDC6I_HUMAN, PDCD6 interacting protein, PDCD6-interacting protein, PDCD6IP, Programmed cell death 6 interacting protein, Programmed cell death 6-interacting protein, AIP1
Also known asPDC6I Polyclonal Antibody
Other nameAnti-PDC6I Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetPDC6I
Short nameAnti-PDC6I (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-PDC6I (polyclonal)
Alternative techniquepolyclonals

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