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Anti-PLB(Ser16) (Polyclonal), ALEXA Fluor 594

Anti-PLB(Ser16) (Polyclonal), ALEXA Fluor 594 size: 100 microliters 516

Price 516
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptidePLB Ser16
SpecificityThis antibody reacts specifically with PLB(Ser16)
ModificationPhosphorylation
Modification siteSer16
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic phosphopeptide derived from human Cardiac phospholamban around the phosphorylation site of Ser16
Gene ID5350
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information CMH18 is a hereditary heart disorder characterized by ventricular hypertrophy, Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, Patients are at risk of premature death, The disorder has inter- and intrafamilial variability ranging from benign to malignant forms with high risk of cardiac failure and sudden cardiac death, The symptoms include dyspnea, They can be readily provoked by exercise, and chest pain, collapse, palpitations, resulting in congestive heart failure and arrhythmia, syncope, which is usually asymmetric and often involves the interventricular septum, Defects in PLN are the cause of cardiomyopathy dilated type 1P (CMD1P) , Defects in PLN are the cause of cardiomyopathy familial hypertrophic type 18 (CMH18)
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms CMD1P
Also known asPLB(Ser16) Polyclonal Antibody
Other nameAnti-PLB(Ser16) Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetPLB(Ser16)
Short nameAnti-PLB(Ser16) (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-PLB(Ser16) (polyclonal)
Alternative techniquepolyclonals
Identity 9080
Gene PLN
Long gene name phospholamban
Synonyms gene PLB
Locus 6q22, 31
Discovery year 1991-08-22
Entrez gene record 5350
Pubmed identfication 1828805
RefSeq identity NM_002667
Havana BLAST/BLAT OTTHUMG00000015462
Locus Specific Databases LRG_390

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