Name : Anti-Pumilio 2 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN8271740307
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | Pumilio 2 |
| Specificity | This antibody reacts specifically with Pumilio 2 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human Pumilio 2 |
| Gene ID | 23369 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | It is also expressed in stem cells, It supports proliferation and self-renewal of stem cells by regulating the translation of key transcripts, Pumilio 2 is highly expressed in testis and ovary and at lower levels in brain, The Pumilio gene encodes proteins that are required for development of germ stem cells in one or both sexes, The Pumilio protein interacts with the human Nanos1 protein and this interaction may play a conserved role in germ cell development, germ cells and in most fetal tissues, heart, intestine and stomach, kidney, liver, muscle, placenta, Pumilio 2 is a sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding mRNA targets |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | PUMH2 KIAA0235 |
| Also known as | Pumilio 2 Polyclonal Antibody |
| Other name | Anti-Pumilio 2 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | Pumilio 2 |
| Short name | Anti-Pumilio 2 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-Pumilio 2 (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 14958 |
| Gene | PUM2 |
| Long gene name | pumilio RNA binding family member 2 |
| Synonyms gene name | pumilio homolog 2 (Drosophila) |
| Locus | 2p24, 1 |
| Discovery year | 2001-03-27 |
| GenBank acession | AF315591 |
| Entrez gene record | 23369 |
| Pubmed identfication | 9039502 12459267 12511597 |
| RefSeq identity | NM_015317 |
| Havana BLAST/BLAT | OTTHUMG00000122098 |