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Anti-RAB7 (Polyclonal), ALEXA Fluor 594

Anti-RAB7 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideRAB7
SpecificityThis antibody reacts specifically with RAB7
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human RAB7
Gene ID7879
Swiss ProtP51149
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Also involved in regulation of some specialized endosomal membrane trafficking, Controls the endosomal trafficking and neurite outgrowth signaling of NTRK1/TRKA, Governs early-to-late endosomal maturation, In concert with RAC1, Microbial pathogens possess survival strategies governed by RAB7A, Mycobacterium), Plays a central role, Plays a role in the fusion of phagosomes with lysosomes, Plays a role in the maturation and acidification of phagosomes that engulf pathogens, Plays important roles in microbial pathogen infection and survival, Regulates the endocytic trafficking of the EGF-EGFR complex by regulating its lysosomal degradation, Salmonella) and sometimes by excluding RAB7A function (e, and endosome-lysosome transport through different protein-protein interaction cascades, as well as in participating in the life cycle of viruses, but also in many other cellular and physiological events, microtubule minus-end as well as plus-end directed endosomal migration and positioning, neurotrophin transport in the axons of neurons and lipid metabolism, not only in endosomal traffic, nutrient-transportor mediated nutrient uptake, pathogen-induced phagosomes (or vacuoles) and autophagosomes, plays a role in regulating the formation of RBs (ruffled borders) in osteoclasts, sometimes by employing RAB7A function (e, such as S, such as growth-factor-mediated cell signaling, such as maturation of melanosomes, Key regulator in endo-lysosomal trafficking, aureus and M, g, g, tuberculosis
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Also known asRAB7 Polyclonal Antibody
Other nameAnti-RAB7 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetRAB7
Short nameAnti-RAB7 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-RAB7 (polyclonal)
Alternative techniquepolyclonals
Identity 9788
Gene RAB7A
Long gene name RAB7A, member RAS oncogene family
Synonyms gene RAB7
Synonyms gene name RAB7, member RAS oncogene family
Locus 3q21, 3
Discovery year 1999-03-24
GenBank acession X93499
Entrez gene record 7879
Pubmed identfication 9126495 9428630
Classification RAB, member RAS oncogene GTPases
Havana BLAST/BLAT OTTHUMG00000159812
Locus Specific Databases LRG_266

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