| Alternative name1 | Anti-Rabbit Polyclonal to Rat FASLG / Fas Ligand |
| Alternative name2 | Rabbit PAb to Rat FASLG / Fas Ligand |
| Alternative name3 | Lapin Polyclonal to Rattus norvegicus FASLG / Fas Ligand |
| Alternative name4 | FASLG / Fas Ligand |
| Alternative name5 | ALPS1B, APT1LG1, APTL, Apoptosis antigen ligand, CD178, CD178 antigen, CD95 ligand, CD95-L, CD95L, FASL, FASLG, Fas Ligand, Fas antigen ligand, Fas ligand, Rat FASLG, TNFSF6, Anti-FASLG / Fas Ligand Antibody (N-Terminus) IHC-plus |
| Other names | APTL, Apoptosis antigen ligand, CD95 ligand, CD95 ligand, CD95-L, CD_antigen: CD178Cleaved into the following 4 chains:Tumor necrosis factor ligand superfamily member 6, Fas antigen ligand, Fas ligand, Fas ligand (TNF superfamily, FasL, Soluble Fas ligand, Tumor necrosis factor ligand superfamily member 6, Tumor necrosis factor ligand superfamily member 6, apoptosis (APO-1) antigen ligand 1, apoptosis antigen ligand, fas antigen ligand, member 6), membrane form, sFasL, soluble formAlternative name(s):Receptor-binding FasL ectodomain, tumor necrosis factor ligand superfamily member 6, tumor necrosis factor ligand superfamily member 6 isoform 1 |
| Gene name | FASLG |
| Gene name synonims | N/A |
| Other gene names | ALPS1B, APL, APT1LG1, APT1LG1, APTL, APTL, CD178, CD95-L, CD95-L, CD95L, CD95L, FASL, FASL, FASLG, Fas ligand, FasL, FasL ICD, SPA, TNFSF6, TNFSF6, sFasL, FASLG |
| Category | Antibodies |
| Clonality | Polyclonal |
| Immunoglobulin isotype | N/A |
| Clone | Polyclonal antibody |
| Host organism | Rabbit |
| Species reactivity | Mouse, Rat, Human |
| Specificity and cross-reactivity | rat and human FAS-L, Mouse |
| Purification method | Immunoaffinity Purified |
| Form/Appearance | 0, 0, 1% sodium azide, 2% gelatin, PBS |
| Concentration | N/A |
| Storage and shipping | Do not freeze, Store at Store productone at +4 degrees Celsius |
| Tested for: | Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Description | Receptor agonists are often tested for drug development, FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| About | Rats , There are less rat- than mouse clones however, Rats are used to make rat monoclonal anti mouse antibodies, Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats, genes from rodents , of the genus |
| Latin name | Rattus norvegicus |
| Gene target | FASLG / Fas Ligand |
| Short name | Anti- FASLG / Fas Ligand Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Host | Rat |
| Species | Rats, Rat |
| Alternative name | member 6) / Fas (TNF receptor superfamily, member 6) Ligand (Antibody to), member 6) ligand (tumor necrosis factor superfamily, antibody to-Rat Fas (TNF receptor superfamily |
| Alternative technique | antibodies |
| Alternative to gene target | ALPS1B and APT1LG1 and APTL and CD178 and CD95-L and CD95L and FASL and TNFSF6, DNA-templated and biological process this GO :0006915 and apoptotic process and biological process this GO :0006919 and activation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0006925 and inflammatory cell apoptotic process and biological process this GO :0006955 and immune response and biological process this GO :0007165 and signal transduction and biological process this GO :0007267 and cell-cell signaling and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008625 and extrinsic apoptotic signaling pathway via death domain receptors and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0016020 and membrane and cellular component this GO :0016023 and cytoplasmic membrane-bounded vesicle and cellular component this GO :0016525 and negative regulation of angiogenesis and biological process this GO :0030644 and cellular chloride ion homeostasis and biological process this GO :0032496 and response to lipopolysaccharide and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0043202 and lysosomal lumen and cellular component this GO :0043525 and positive regulation of neuron apoptotic process and biological process this GO :0045121 and membrane raft and cellular component this GO :0045742 and positive regulation of epidermal growth factor receptor signaling pathway and biological process this GO :0046666 and retinal cell programmed cell death and biological process this GO :0048388 and endosomal lumen acidification and biological process this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0060205 and cytoplasmic membrane-bounded vesicle lumen and cellular component this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070231 and T cell apoptotic process and biological process this GO :0070266 and necroptotic process and biological process this GO :0070848 and response to growth factor and biological process this GO :0097190 and apoptotic signaling pathway and biological process this GO :0097191 and extrinsic apoptotic signaling pathway and biological process this GO :0097527 and necroptotic signaling pathway and biological process this GO :2000353 and positive regulation of endothelial cell apoptotic process and biological process this GO :2001239 and regulation of extrinsic apoptotic signaling pathway in absence of ligand and biological process, FASLG and IDBG-104856 and ENSG00000117560 and 356, Fasl and IDBG-201576 and ENSMUSG00000000817 and 14103, LOC407111 and IDBG-632305 and ENSBTAG00000032808 and 101908770, member 6), nuclei, protein binding, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0005102 and receptor binding and molecular function this GO :0005123 and death receptor binding and molecular function this GO :0005125 and cytokine activity and molecular function this GO :0005164 and tumor necrosis factor receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005634 and nucleus and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0005901 and caveola and cellular component this GO :0006351 and transcription, this GO :0005102: receptor binding, this GO :0005102: receptor binding and also this GO :0005123: death receptor binding and also this GO :0005125: cytokine activity and also this GO :0005164: tumor necrosis factor receptor binding and also this GO :0005515: protein binding, this GO :0005123: death receptor binding, this GO :0005125: cytokine activity, this GO :0005164: tumor necrosis factor receptor binding, this GO :0005515: protein binding, 407111, Fas ligand (TNF superfamily |
| Identity | 11936 |
| Gene | FASLG |
| Long gene name | Fas ligand |
| Synonyms gene | APT1LG1 TNFSF6 |
| Synonyms gene name | member 6 Fas ligand (TNF superfamily, member 6) , tumor necrosis factor (ligand) superfamily |
| Synonyms | FasL CD178 |
| Locus | 1q24, 3 |
| Discovery year | 1994-12-09 |
| GenBank acession | U11821 |
| Entrez gene record | 356 |
| Pubmed identfication | 7826947 9022072 |
| Classification | Endogenous ligands Tumor necrosis factor superfamily CD molecules Death inducing signaling complex |
| Havana BLAST/BLAT | OTTHUMG00000034841 |
| Locus Specific Databases | FASLGbase: Mutation registry for Autoimmune lymphoproliferative syndrome, type 1B (ALPS1B) (previously known as TNFSF6base) LRG_58 |
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