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Anti-Reticulon 4 (Polyclonal), ALEXA Fluor 594

Anti-Reticulon 4 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideReticulon 4
Specificity Nogo-B, and Nogo-C), Based on the location of the target sequence this antibody will recognize all isoforms(Nogo-A, Reticulon 4
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsCytoplasm
Antigen SourceKLH conjugated synthetic peptide derived from Mouse Reticulon 4
Gene ID68585
Swiss ProtQ99P72
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Developmental neurite growth regulatory factor with a role as a negative regulator of axon-axon adhesion and growth, Involved in down-regulation of growth, It regulates the radial migration of cortical neurons via an RTN4R-LINGO1 containing receptor complex, May inhibit BACE1 activity and amyloid precursor protein processing, Reticulon 4 regulates neurite fasciculation, The reticulon protein is a potent neurite outgrowth inhibitor which may also help block the regeneration of the central nervous system in higher vertebrates, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells, and as a facilitator of neurite branching, branching and extension in the developing nervous system, stabilization of wiring and restriction of plasticity in the adult CNS, Reticulons are associated with the endoplasmic reticulum
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms NOGOR
Also known asReticulon 4 Polyclonal Antibody
Other nameAnti-Reticulon 4 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetReticulon 4
Short nameAnti-Reticulon 4 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-Reticulon 4 (polyclonal)
Alternative techniquepolyclonals
Identity 18601
Gene RTN4R
Long gene name reticulon 4 receptor
Locus 22q11, 21
Discovery year 2002-04-30
GenBank acession AF283463
Entrez gene record 65078
Pubmed identfication 11201742
Havana BLAST/BLAT OTTHUMG00000150572

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