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Anti-RIN1 (Polyclonal), ALEXA Fluor 594

Anti-RIN1 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideRIN1
SpecificityThis antibody reacts specifically with RIN1
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human RIN1
Gene ID9610
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information It enhances signaling from ABL1 and ABL2 whcih are involved in regulation of cytoskeletal remodeling, It may function as a guanine nucleotide exchange factor in activation of Rab5a, It may play a role inhibiting the modulation of neuronal plasticity in formation of aversive memory, Rin1 also competes with RAF1 for binding of the activated form of Ras, and has been implicated as a tumor supressor gene in breast cancer, RIN1 is a Ras effector protein which can affect Ras signaling in a variety of ways
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Also known asRIN1 Polyclonal Antibody
Other nameAnti-RIN1 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetRIN1
Short nameAnti-RIN1 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-Ras and Rab interactor 1 (polyclonal)
Alternative techniquepolyclonals
Alternative to gene target Plasma membranes, RIN1 and IDBG-58865 and ENSG00000174791 and 9610, RIN1 and IDBG-644375 and ENSBTAG00000017681 and 509295, Ras GTPase binding, Rin1 and IDBG-130658 and ENSMUSG00000024883 and 225870, this GO :0005096 and GTPase activator activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005856 and cytoskeleton and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006897 and endocytosis and biological process this GO :0007165 and signal transduction and biological process this GO :0007613 and memory and biological process this GO :0008306 and associative learning and biological process this GO :0017016 and Ras GTPase binding and molecular function this GO :0030425 and dendrite and cellular component this GO :0031914 and negative regulation of synaptic plasticity and biological process this GO :0043025 and neuronal cell body and cellular component this GO :0043547 and positive regulation of GTPase activity and biological process, this GO :0005096: GTPase activator activity, this GO :0005096: GTPase activator activity and also this GO :0005515: protein binding and also this GO :0017016: Ras GTPase binding, this GO :0005515: protein binding, this GO :0017016: Ras GTPase binding, Ras and Rab interactor 1
Identity 18749
Gene RIN1
Long gene name Ras and Rab interactor 1
Locus 11q13, 2
Discovery year 2002-09-11
GenBank acession L36463
Entrez gene record 9610
Pubmed identfication 9144171 1849280
RefSeq identity NM_004292
Classification VPS9 domain containing
Havana BLAST/BLAT OTTHUMG00000167085

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