Name : Anti-RIN1 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN6752953174
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | RIN1 |
| Specificity | This antibody reacts specifically with RIN1 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human RIN1 |
| Gene ID | 9610 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | It enhances signaling from ABL1 and ABL2 whcih are involved in regulation of cytoskeletal remodeling, It may function as a guanine nucleotide exchange factor in activation of Rab5a, It may play a role inhibiting the modulation of neuronal plasticity in formation of aversive memory, Rin1 also competes with RAF1 for binding of the activated form of Ras, and has been implicated as a tumor supressor gene in breast cancer, RIN1 is a Ras effector protein which can affect Ras signaling in a variety of ways |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Also known as | RIN1 Polyclonal Antibody |
| Other name | Anti-RIN1 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | RIN1 |
| Short name | Anti-RIN1 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-Ras and Rab interactor 1 (polyclonal) |
| Alternative technique | polyclonals |
| Alternative to gene target | Plasma membranes, RIN1 and IDBG-58865 and ENSG00000174791 and 9610, RIN1 and IDBG-644375 and ENSBTAG00000017681 and 509295, Ras GTPase binding, Rin1 and IDBG-130658 and ENSMUSG00000024883 and 225870, this GO :0005096 and GTPase activator activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005856 and cytoskeleton and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006897 and endocytosis and biological process this GO :0007165 and signal transduction and biological process this GO :0007613 and memory and biological process this GO :0008306 and associative learning and biological process this GO :0017016 and Ras GTPase binding and molecular function this GO :0030425 and dendrite and cellular component this GO :0031914 and negative regulation of synaptic plasticity and biological process this GO :0043025 and neuronal cell body and cellular component this GO :0043547 and positive regulation of GTPase activity and biological process, this GO :0005096: GTPase activator activity, this GO :0005096: GTPase activator activity and also this GO :0005515: protein binding and also this GO :0017016: Ras GTPase binding, this GO :0005515: protein binding, this GO :0017016: Ras GTPase binding, Ras and Rab interactor 1 |
| Identity | 18749 |
| Gene | RIN1 |
| Long gene name | Ras and Rab interactor 1 |
| Locus | 11q13, 2 |
| Discovery year | 2002-09-11 |
| GenBank acession | L36463 |
| Entrez gene record | 9610 |
| Pubmed identfication | 9144171 1849280 |
| RefSeq identity | NM_004292 |
| Classification | VPS9 domain containing |
| Havana BLAST/BLAT | OTTHUMG00000167085 |