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Anti-RNF92 (Polyclonal), ALEXA Fluor 594

Anti-RNF92 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideRNF92
SpecificityThis antibody reacts specifically with RNF92
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human TRIM11/RNF92
Gene ID81559
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Antiviral activity depends on a functional E3 ubiquitin-protein ligase domain, May also inhibit PAX6 transcriptional activity, May contribute to the innate restriction of retroviruses, May contribute to the regulation of the intracellular level of HN (humanin) or HN-containing proteins through the proteasomal degradation pathway, May regulate TRIM5 turnover via the proteasome pathway, Mediates MED15 ubiquitination leading to proteasomal degradation, Mediates PAX6 ubiquitination leading to proteasomal degradation, Upon overexpression, by suppressing viral gene expression, including insoluble PAX6, poly-Gln repeat expanded HTT and poly-Ala repeat expanded ARX, possibly in part by preventing the binding of PAX6 to its consensus sequences, reduces HIV-1 and murine leukemia virus infectivity, thereby modulating cortical neurogenesis, thus counteracting the TRIM5-mediated cross-species restriction of retroviral infection at early stages of the retroviral life cycle, E3 ubiquitin-protein ligase that promotes the degradation of insoluble ubiquitinated proteins
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms RNF92 BIA1
Also known asRNF92 Polyclonal Antibody
Other nameAnti-RNF92 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetRNF92
Short nameAnti-RNF92 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-RNF92 (polyclonal)
Alternative techniquepolyclonals
Identity 16281
Gene TRIM11
Long gene name tripartite motif containing 11
Synonyms gene name tripartite motif-containing 11
Locus 1q42, 13
Discovery year 2001-08-07
GenBank acession AF220125
Entrez gene record 81559
Pubmed identfication 11331580
RefSeq identity NM_145214
Classification Tripartite motif containing Ring finger proteins
Havana BLAST/BLAT OTTHUMG00000039773

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