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Anti-Ryanodine Receptor (Polyclonal), ALEXA Fluor 594

Anti-Ryanodine Receptor (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideRyanodine Receptor
Specificity Ryanodine Receptor 2, and Ryanodine Receptor 3Ryanodine Receptor, This antibody will recognize Ryanodine Receptor 1
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsCytoplasm
Antigen SourceKLH conjugated synthetic peptide derived from human Ryanodine Receptor
Gene ID6261, 6262, 6263
Swiss Prot Q15413, Q92736, P21817
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information In non-mammalian vertebrates, Mammalian RyR isoforms are the product of three different genes: RyR-1 is expressed predominantly in skeletal muscle and areas of the brain, RyR-2 is expressed predominantly in heart muscle but also found in the stomach, RyR-3 and RyR-2 isoforms respectively, The RyR exists as a homotetramer and is predicted to have a short cytoplasmic C-terminus and 4-10 transmembrane domains, The remainder of the protein, and RyR-3 is found in smooth muscle and the brain (striatum, beta and cardiac which correlate loosely to the mammalian RyR-1, endothelial cells and diffuse areas of the brain, is located in the cytoplasm between the transverse tubule and the SR, region, termed the ", thalamus and hippocampus), the RyR isoforms are termed alpha, The Ryanodine Receptor (RyR) is the channel responsible for calcium release from muscle cell Sarcoplasmic Reticulum (SR) and also plays a role in calcium regulation in non-muscle cells, foot"
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Also known asRyanodine Receptor Polyclonal Antibody
Other nameAnti-Ryanodine Receptor Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetRyanodine Receptor
Short nameAnti-Ryanodine Receptor (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-Ryanodine Receptor (polyclonal)
Alternative techniquepolyclonals
Identity 10485
Gene RYR3
Long gene name ryanodine receptor 3
Locus 15q13, 3-q14
Discovery year 1993-05-12
Entrez gene record 6263
Pubmed identfication 8276408
Classification Ryanodine receptors EF-hand domain containing
Havana BLAST/BLAT OTTHUMG00000172253

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