Filters

Anti-SAMHD1 (Polyclonal), ALEXA Fluor 594

Anti-SAMHD1 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideSAMHD1
SpecificityThis antibody reacts specifically with SAMHD1
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human SAMHD1
Gene ID4861
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information A form of Aicardi-Goutieres syndrome, Clinical features as thrombocytopenia, Death often occurs in early childhood, May play a role in mediating proinflammatory responses to TNF-alpha signaling, No expression is seen in brain and thymus, Severe neurological dysfunctions manifest in infancy as progressive microcephaly, a genetically heterogeneous disease characterized by cerebral atrophy, and negative serologic investigations for common prenatal infection, chronic cerebrospinal fluid (CSF) lymphocytosis, dystonic posturing and profound psychomotor retardation, hepatosplenomegaly and elevated hepatic transaminases along with intermittent fever may erroneously suggest an infective process, increased CSF alpha-interferon, intracranial calcifications, leukoencephalopathy, liver, lung and peripheral blood leukocytes, placenta, skeletal muscle, small intestine, spasticity, spleen, Involvement in disease:Defects in SAMHD1 are the cause of Aicardi-Goutieres syndrome type 5 (AGS5) , Putative nuclease involved in innate immune response by acting as a negative regulator of the cell-intrinsic antiviral response, Tissue specificity:Expressed in heart
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms SBBI88 Mg11 HDDC1 MOP-5 AGS5
Also known asSAMHD1 Polyclonal Antibody
Other nameAnti-SAMHD1 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetSAMHD1
Short nameAnti-SAMHD1 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-SAMHD1 (polyclonal)
Alternative techniquepolyclonals
Identity 15925
Gene SAMHD1
Long gene name SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1
Synonyms gene name SAM domain and HD domain 1
Synonyms name HD domain containing 1 monocyte protein 5 Aicardi-Goutieres syndrome 5
Locus 20q11, 23
Discovery year 2001-07-31
GenBank acession AF228421
Entrez gene record 25939
Pubmed identfication 11064105 11230166 22056990
RefSeq identity NM_015474
Classification Sterile alpha motif domain containing
Havana BLAST/BLAT OTTHUMG00000032402
Locus Specific Databases LRG_281

Similar products

Subscribe to our Newsletter