Filters

Anti-Separase (Ser1073) (Polyclonal), ALEXA Fluor 594

Anti-Separase (Ser1073) (Polyclonal), ALEXA Fluor 594 size: 100 microliters 516

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 516
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideSeparase Ser1073
SpecificityThis antibody reacts specifically with Separase (Ser1073)
ModificationPhosphorylation
Modification siteSer1073
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic phosphopeptide derived from human ESPL1 around the phosphorylation site of Ser1073
Gene ID9700
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive speciesHuman (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information As the cellular division process continues, Cohesin plays an important role in cohering sister chromatids during the prophase through anaphase stages of mitosis, Each cell must receive one chromatid of every chromosome, It not only cleaves cohesin at the onset of anaphase but also cleaves itself, Separase activity is highly regulated, Should a human cell become an aneuploid (one too many or too few chromatids), Should the embryo survive, allowing the chromatids to separate and divide with the cell, during mitosis, it will most likely develop severe birth defects or later develop malignant cancers, making certain that genomic information is replicated accurately, promoting downregulation of separase after anaphase, separase destroys cohesin by means of cleavage, the embryo most likely will not survive, Separase is a cysteine protease that is essential for mitotic progression by separating sister chromatids
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms ESP 1, ESP-1, ESP1, ESPL 1, ESPL-1, ESPL1, ESPL1_HUMAN, Extra spindle poles like 1, Extra spindle poles like 1 protein, SSE, Separase, Separin, Similar to fission yeast cut1and gene, Caspase like protein ESPL1
Also known asSeparase (Ser1073) Polyclonal Antibody
Other nameAnti-Separase (Ser1073) Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetSeparase (Ser1073)
Short nameAnti-Separase (Ser1073) (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-Separase (Ser1073) (polyclonal)
Alternative techniquepolyclonals

Similar products

Subscribe to our Newsletter