Name : Anti-SMMHC/Myosin (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN4052441275
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | SMMHC/Myosin |
| Specificity | This antibody reacts specifically with SMMHC/Myosin |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | Cytoplasm |
| Antigen Source | KLH conjugated synthetic peptide derived from human SMHC |
| Gene ID | 4629 |
| Swiss Prot | P35749 |
| Applications | IF(ICC), IF(IHC-P) |
| Applications with corresponding dilutions | IF(ICC)(1:50-200), IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Alternative splicing generates isoforms that are differentially expressed, Alternatively spliced transcript variants encoding different isoforms have been identified, It functions as a major contractile protein, It functions as a major contractile protein, It is a subunit of a hexameric protein that consists of two heavy chain subunits and two pairs of non-identical light chain subunits, MYH11 is a smooth muscle myosin belonging to the myosin heavy chain family, The gene encoding a human ortholog of rat NUDE1 is transcribed from the reverse strand of this gene, The gene product is a subunit of a hexameric protein that consists of two heavy chain subunits and two pairs of non-identical light chain subunits, The pericentric inversion of chromosome 16[inv(16)(p13q22)] produces a chimeric transcript that encodes a protein consisting of the first 165 residues from the N terminus of core-binding factor beta in a fusion with the C-terminal portion of the smooth muscle myosin heavy chain, This chromosomal rearrangement is associated with acute myeloid leukemia of the M4Eo subtype, and its 3' end overlaps with that of the latter, converting chemical energy into mechanical energy through the hydrolysis of ATP, converting chemical energy into mechanical energy through the hydrolysis of ATP, with ratios changing during muscle cell maturation, The protein encoded by this gene is a smooth muscle myosin belonging to the myosin heavy chain family |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | SMMHC SMHC |
| Also known as | SMMHC/Myosin Polyclonal Antibody |
| Other name | Anti-SMMHC/Myosin Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | SMMHC/Myosin |
| Short name | Anti-SMMHC/Myosin (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-SMMHC/Myosin (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 7569 |
| Gene | MYH11 |
| Long gene name | myosin heavy chain 11 |
| Synonyms gene name | heavy polypeptide 11, myosin, smooth muscle |
| Locus | 16p13, 11 |
| Discovery year | 1991-09-13 |
| GenBank acession | X69292 |
| Entrez gene record | 4629 |
| Pubmed identfication | 7684189 |
| RefSeq identity | NM_001040113 |
| Classification | Myosin heavy chains |
| Havana BLAST/BLAT | OTTHUMG00000129935 |