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Anti-SMURF1 (Polyclonal), ALEXA Fluor 594

Anti-SMURF1 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideSMURF1
SpecificityThis antibody reacts specifically with SMURF1
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human SMURF1
Gene ID57154
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information 2 receptor-regulated SMADs specific for the BMP pathway, Acts by mediating ubiquitination and degradation of SMAD1 and SMAD5, Promotes ubiquitination and subsequent proteasomal degradation of TRAF family members, E3 ubiquitin-protein ligase that acts as a negative regulator of BMP signaling pathway
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms KIAA1625
Also known asSMURF1 Polyclonal Antibody
Other nameAnti-SMURF1 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetSMURF1
Short nameAnti-SMURF1 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-SMAD specific E3 ubiquitin protein ligase 1 (polyclonal)
Alternative techniquepolyclonals
Alternative to gene target R-SMAD binding, SMURF1 and IDBG-28871 and ENSG00000198742 and 57154, SMURF1 and IDBG-640859 and ENSBTAG00000007118 and, Smurf1 and IDBG-208404 and ENSMUSG00000038780 and 75788, nuclei, this GO :0000209 and protein polyubiquitination and biological process this GO :0004842 and ubiquitin-protein transferase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006611 and protein export from nucleus and biological process this GO :0007179 and transforming growth factor beta receptor signaling pathway and biological process this GO :0007398 and ectoderm development and biological process this GO :0016567 and protein ubiquitination and biological process this GO :0016874 and ligase activity and molecular function this GO :0030154 and cell differentiation and biological process this GO :0030279 and negative regulation of ossification and biological process this GO :0030424 and axon and cellular component this GO :0030509 and BMP signaling pathway and biological process this GO :0030512 and negative regulation of transforming growth factor beta receptor signaling pathway and biological process this GO :0030514 and negative regulation of BMP signaling pathway and biological process this GO :0030579 and ubiquitin-dependent SMAD protein catabolic process and biological process this GO :0032801 and receptor catabolic process and biological process this GO :0034394 and protein localization to cell surface and biological process this GO :0042787 and protein ubiquitination involved in ubiquitin-dependent protein catabolic process and biological process this GO :0043025 and neuronal cell body and cellular component this GO :0043161 and proteasome-mediated ubiquitin-dependent protein catabolic process and biological process this GO :0048185 and activin binding and molecular function this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070411 and I-SMAD binding and molecular function this GO :0070412 and R-SMAD binding and molecular function, this GO :0004842: ubiquitin-protein transferase activity, this GO :0004842: ubiquitin-protein transferase activity and also this GO :0005515: protein binding and also this GO :0016874: ligase activity and also this GO :0048185: activin binding and also this GO :0070411: I-SMAD binding and also this GO :0070412: R-SMAD binding, this GO :0005515: protein binding, this GO :0016874: ligase activity, this GO :0048185: activin binding, this GO :0070411: I-SMAD binding, this GO :0070412: R-SMAD binding, SMAD specific E3 ubiquitin protein ligase 1
Identity 16807
Gene SMURF1
Long gene name SMAD specific E3 ubiquitin protein ligase 1
Locus 7q22, 1
Discovery year 2004-07-29
GenBank acession AB046845
Entrez gene record 57154
Pubmed identfication 10458166
RefSeq identity NM_020429
Havana BLAST/BLAT OTTHUMG00000150272

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