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Anti-Tie2 (Tyr992) (Polyclonal), ALEXA Fluor 594

Anti-Tie2 (Tyr992) (Polyclonal), ALEXA Fluor 594 size: 100 microliters 516

Price 516
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideTie2 Tyr992
SpecificityThis antibody reacts specifically with Tie2 (Tyr992)
ModificationPhosphorylation
Modification siteTyr992
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic phosphopeptide derived from human Tie2 around the phosphorylation site of Tyr992
Gene ID7010
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Defects in TEK are associated with inherited venous malformations, The ligand for the receptor is angiopoietin-1, This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats, and humans, rats, the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis, TEK is closely related to the TIE receptor tyrosine kinase, The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms Angiopoietin 1 receptor, Angiopoietin-1 receptor, CD202b, CD202b, CD202b antigen, Endothelial tyrosine kinase, Endothelium specic receptor tyrosine kinase 2, Hyk, Soluble TIE2 variant 1, Soluble TIE2 variant 2, TEK tyrosine kinase endothelial, TIE 2, TIE2_HUMAN, Tek, Tie2, Tunica interna endothelial cell kinase, Tunica interna endothelial cell kinase, Tyrosine kinase with Ig and EGF homology domains 2, Tyrosine protein kinase receptor TEK, Tyrosine protein kinase receptor TIE 2, Tyrosine-protein kinase receptor TEK, Tyrosine-protein kinase receptor TIE-2, Tyrosine-protein kinase receptor TIE-2, VMCM, VMCM 1, VMCM1, Venous malformations multiple cutaneous and mucosal, endothelial, hTIE 2, hTIE2, p140 TEK, tek tyrosine kinase, tek tyrosine kinase, Tie-2
Also known asTie2 (Tyr992) Polyclonal Antibody
Other nameAnti-Tie2 (Tyr992) Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetTie2 (Tyr992)
Short nameAnti-Tie2 (Tyr992) (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-Tie2 (Tyr992) (polyclonal)
Alternative techniquepolyclonals

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