Name : Anti-TTC21B (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN7655320452
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | TTC21B |
| Specificity | This antibody reacts specifically with TTC21B |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human TTC21B |
| Gene ID | N/A |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | 34 amino acid sequence found in many proteins and acts to mediate protein-protein interactions in various pathways, At the sequence level, Localizing to cytoplasm and cytoskeleton, TTC21B (tetratricopeptide repeat domain 21B), TTC21B exists as two alternatively spliced isoforms and is thought to negatively regulate Shh signal transduction, TTC21B may also be involved in retrograde intraflagellar transport in cilia, also known as THM1, and is encoded by a gene that maps to human chromosome 2q24, each of which has a helix-turn-helix shape that stacks on other TPR repeats to achieve ligand binding specificity, is a 1, there can be up to 16 tandem TPR repeats, 3, 316 amino acid protein that contains 19 TPR repeats and belongs to the TTC21 family, The tetratricopeptide repeat (TPR) motif is a degenerate |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | FLJ11457 JBTS11 NPHP12 IFT139B THM1 |
| Also known as | TTC21B Polyclonal Antibody |
| Other name | Anti-TTC21B Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | TTC21B |
| Short name | Anti-TTC21B (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-TTC21B (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 25660 |
| Gene | TTC21B |
| Long gene name | tetratricopeptide repeat domain 21B |
| Locus | 2q24, 3 |
| Discovery year | 2005-01-26 |
| GenBank acession | AB082523 |
| Entrez gene record | 79809 |
| Pubmed identfication | 12056414 21258341 |
| RefSeq identity | NM_024753 |
| Classification | Intraflagellar transport proteins Tetratricopeptide repeat domain containing |
| Havana BLAST/BLAT | OTTHUMG00000154083 |