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Anti-TTC21B (Polyclonal), ALEXA Fluor 594

Anti-TTC21B (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideTTC21B
SpecificityThis antibody reacts specifically with TTC21B
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human TTC21B
Gene IDN/A
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information 34 amino acid sequence found in many proteins and acts to mediate protein-protein interactions in various pathways, At the sequence level, Localizing to cytoplasm and cytoskeleton, TTC21B (tetratricopeptide repeat domain 21B), TTC21B exists as two alternatively spliced isoforms and is thought to negatively regulate Shh signal transduction, TTC21B may also be involved in retrograde intraflagellar transport in cilia, also known as THM1, and is encoded by a gene that maps to human chromosome 2q24, each of which has a helix-turn-helix shape that stacks on other TPR repeats to achieve ligand binding specificity, is a 1, there can be up to 16 tandem TPR repeats, 3, 316 amino acid protein that contains 19 TPR repeats and belongs to the TTC21 family, The tetratricopeptide repeat (TPR) motif is a degenerate
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms FLJ11457 JBTS11 NPHP12 IFT139B THM1
Also known asTTC21B Polyclonal Antibody
Other nameAnti-TTC21B Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetTTC21B
Short nameAnti-TTC21B (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-TTC21B (polyclonal)
Alternative techniquepolyclonals
Identity 25660
Gene TTC21B
Long gene name tetratricopeptide repeat domain 21B
Locus 2q24, 3
Discovery year 2005-01-26
GenBank acession AB082523
Entrez gene record 79809
Pubmed identfication 12056414 21258341
RefSeq identity NM_024753
Classification Intraflagellar transport proteins Tetratricopeptide repeat domain containing
Havana BLAST/BLAT OTTHUMG00000154083

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