Name : Anti-Ube2G1 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN8385753725
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | Ube2G1 |
| Specificity | This antibody reacts specifically with Ube2G1 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human Ube2G1/UBC7 |
| Gene ID | 7326 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Rat (Rattus norvegicus), Mouse (Mus musculus) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | E1 first transfers ubiquitin to the E2 component Ubc4, In Saccharomyces cerevisiae, In this fashion, In this particular reaction, Rub1 shares 53% homology with ubiquitin and requires activation via the E2 proteins, Smt3, The primary function of ubiquitin in mammalian systems is to clear abnormal, Uba3, Uba3 and Ubc12 in order to conjugate to substrates directed to different proteolytic systems, Ubc12 and Ubc9, Ubc2, Ubc4 catalyzes ubiquitination of IkBa in a phosphorylation and SCFB-TRCP dependent manner, Ula1, and Ubc4 then associates with E3 ligase, and improperly folded proteins by targeting them for proteosome degradation, foreign, highly conserved protein found in all eukaryotic cells either free or covalently attached to cellular proteins, including Ula1, the chain tags the IkBa for degradation by a proteasome thus lifting the inhibitory effect of IkBa on NFkB and allowing NFkB to enter the nucleus, ubiquitin-like proteins include Rub1, which conjugates the poly-ubiquitin chain on a target protein, Ubiquitin is an abundant |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | UBC7 UBE2G1 |
| Also known as | Ube2G1 Polyclonal Antibody |
| Other name | Anti-Ube2G1 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | Ube2G1 |
| Short name | Anti-Ube2G1 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-Ube2G1 (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 12481 |
| Gene | UBE2G |
| Long gene name | ubiquitin conjugating enzyme E2 G1 |
| Synonyms gene name | C, elegans UBC7) ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, elegans) ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, ubiquitin-conjugating enzyme E2G 1 (homologous to C, yeast) ubiquitin-conjugating enzyme E2G 1 |
| Locus | 17p13, 2 |
| Discovery year | 1996-05-15 |
| GenBank acession | BC026288 |
| Entrez gene record | 7326 |
| Pubmed identfication | 8893823 |
| RefSeq identity | NM_003342 |
| Classification | Ubiquitin conjugating enzymes E2 |
| Havana BLAST/BLAT | OTTHUMG00000177826 |