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Anti-UVRAG (Polyclonal), ALEXA Fluor 594

Anti-UVRAG (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideUVRAG
SpecificityThis antibody reacts specifically with UVRAG
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human UVRAG/DHTX
Gene ID7405
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Autophagy is the degradation of cellular proteins in the lysosomes, Mutations in the gene encoding UVRAG have been associated with colon cancer, UVRAG contains one C2 domain, UVRAG has been found to complement the ultraviolet sensitivity of xeroderma pigmentosum group C cells, UVRAG has been shown to activate the BECN1/PI 3-kinase complex, UVRAG is found at highest levels in kidney, Ubiquitously expressed, also known as p63 or DHTX, and when this pathway is suppressed, cell growth is deregulated, is a 699 amino acid cytoplasmic protein, liver and brain, lung, suggesting that UVRAG is also involved in suppressing the proliferation and tumorigenicity of human colon cancer cells, which is thought to be involved in calcium-dependent phospholipid binding, which promotes autophagy, UVRAG
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms VPS38
Also known asUVRAG Polyclonal Antibody
Other nameAnti-UVRAG Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetUVRAG
Short nameAnti-UVRAG (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-UVRAG (polyclonal)
Alternative techniquepolyclonals
Identity 12640
Gene UVRAG
Long gene name UV radiation resistance associated
Synonyms gene name UV radiation resistance associated gene
Synonyms name beclin 1 binding protein
Locus 11q13, 5
Discovery year 1997-01-10
GenBank acession X99050 AB012958
Entrez gene record 7405
Pubmed identfication 9169138 16799551 18843052
RefSeq identity NM_003369
Classification C2 domain containing
Havana BLAST/BLAT OTTHUMG00000165319

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