Name : Anti-ZNF131 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN5882130497
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | ZNF131 |
| Specificity | This antibody reacts specifically with ZNF131 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human ZNF131 |
| Gene ID | 7690 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | As a member of the krueppel C2H2-type zinc-finger protein family, The majority of zinc-finger proteins contain a Kruppel-type DNA binding domain and a KRAB domain, There are two isoforms of ZNF131 that are produced as a result of alternative splicing events, With predominant expression found in brain, ZNF131 (Zinc finger protein 131) is a 623 amino acid nuclear protein that contains one BTB (POZ) domain and six C2H2-type zinc fingers, ZNF131 also represses ER Alpha (Estrogen receptor alpha)-mediated transactivation by interrupting ER?binding to the estrogen-response element, it is likely that ZNF131 plays a role as a transcription regulator during development and organogenesis of the adult central nervous system, most of which encompass some form of transcriptional activation or repression, thereby recruiting histone modifying proteins, which is thought to interact with KAP1, Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | ZBTB35 pHZ-10 |
| Also known as | ZNF131 Polyclonal Antibody |
| Other name | Anti-ZNF131 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | ZNF131 |
| Short name | Anti-ZNF131 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-ZNF131 (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 12915 |
| Gene | ZNF131 |
| Long gene name | zinc finger protein 131 |
| Synonyms gene name | zinc finger protein 131 (clone pHZ-10) |
| Synonyms name | zinc finger and BTB domain containing 35 |
| Locus | 5p12 |
| Discovery year | 1993-02-11 |
| GenBank acession | U09410 |
| Entrez gene record | 7690 |
| RefSeq identity | NM_003432 |
| Classification | BTB domain containing Zinc fingers C2H2-type |
| Havana BLAST/BLAT | OTTHUMG00000162223 |