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APEX1 Antibody (APE1)

APEX1 Antibody (APE1) size: 0.1mg 389

Supplier NJS POLY
Price 389
Size 0.1mg
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenAPEX1 (APE1)
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications IHC-P, WB
Recommended dilutions5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0
Notes Titration of the APEX1 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts
Intented useThis APE1 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P27695
PurityAntigen affinity
Description The abundance of the large form of the protein was increased in leiomyoma extracts relative to myometrial tissue extracts, The exonuclease activity of nuclear APEX1 can remove the anti-HIV nucleoside analogs AZT and D4T from the 3-prime terminus of a nick more efficiently than can cytosolic exonucleases, and the large form was dominant in cell lines derived from leiomyosarcomas, or Apurinic endonuclease 1 (APE1), was identified as a member of a family of DNA repair enzymes found in lower organisms, which contains probable nuclear transport signals, APEX1
Immunogen mouse and rat), An amino acid sequence from the middle region of human APEX1 (RGLVRLEYRQRWDEA) was used as the immunogen for this APEX1 antibody (100% homologous in human
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the APEX1 antibody can be stored for up to one month at 4oC, After reconstitution
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetAPEX1 (APE1)
Short nameAPEX1 Antibody (APE1)
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameAPEX1 (Antibody to) (APE1)
Alternative techniqueantibodies
Identity 587
Gene APEX1
Long gene name apurinic/apyrimidinic endodeoxyribonuclease 1
Synonyms gene APEX
Synonyms gene name APEX nuclease (multifunctional DNA repair enzyme) APEX nuclease (multifunctional DNA repair enzyme) 1
Synonyms APE REF1 HAP1 APX APEN REF-1 APE-1
Locus 14q11, 2
Discovery year 1997-05-22
GenBank acession X59764
Entrez gene record 328
RefSeq identity NM_001641
Havana BLAST/BLAT OTTHUMG00000029544
Locus Specific Databases ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database

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