Filters

APOBEC3C Antibody, FITC Conjugated

APOBEC3C Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, APOBEC3C Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenAPOBEC3C
SpecificityThis is a highly specific antibody against APOBEC3C
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human APOBEC3C
Gene ID number27350
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
CrossreactivityHuman
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background APOBEC3F deaminates deoxycytosine to deoxyuracil in the minus strand of HIV-1 DNA, APOBEC3G and APOBEC3F provide a mechanism for innate immunity to retroviruses, HIV-1 Vif cannot form a complex with APOBEC3G or APOBEC3F of mouse origin as it does with the human protein, Interestingly, Like APOBEC3G, The seven APOBEC3 genes or pseudogenes are found in a cluster thought to result from gene duplication on chromosome 22, This implies that induction of APOBEC3G and APOBEC3F activity or a method of blocking their interaction with Vif may provide a method for therapeutic intervention, Thus, Viral infectivity factor (Vif) imparts APOBEC3G and APOBEC3F resistance to HIV through impaired translation of their mRNA and accelerated posttranslational degradation of the APOBEC3 proteins by the 26S proteasome, and are also likely contribute to sequence variation observed in many viruses, and thus mouse APOBEC3G and APOBEC3F function as a potent inhibitors of wildtype HIV-1 replication, resulting in G to A hypermutation in the plus strand of DNA, where human APOBEC3G and APOBEC3F are only able to inhibit Vif-deficient HIV-1 replication, APOBEC proteins inhibit retroviruses by deaminating cytosine residues of viral RNA and DNA
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms APOBEC1L PBI bK150C2, 3 ARDC2 ARDC4 ARP5
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetAPOBEC3C Conjugated
Short name FITC Conjugated, APOBEC3C Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, APOBEC3C (Antibody to)
Alternative techniqueantibodies
Identity 17353
Gene APOBEC3C
Long gene name apolipoprotein B mRNA editing enzyme catalytic subunit 3C
Synonyms gene name apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
Locus 22q13, 1
Discovery year 2001-12-12
GenBank acession AF165520
Entrez gene record 27350
Pubmed identfication 11863358
RefSeq identity NM_014508
Classification Apolipoprotein B mRNA editing enzyme catalytic subunits
Havana BLAST/BLAT OTTHUMG00000151087

Similar products

Subscribe to our Newsletter