| Long name | APOE Primary Polyclonal Antibody |
| Also known as | APOE PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | APOE |
| Specificity | This is a highly specific antibody against APOE |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 230-280/311 |
| Subcellular location | Secreted |
| Source | KLH conjugated synthetic peptide derived from mouse Apo E |
| Gene ID number | 11816 |
| Swiss Prot | P08226 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Rat, Mouse |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | It can serve as a ligand for the LDL (apo B/E) receptor and for the specific apo-E receptor (chylomicron remnant) of hepatic tissues, and catabolism of lipoprotein particles, internalization, Mediates the binding |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | AI255918, Apoe, Apolipoprotein E, Apo-E |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | APOE |
| Short name | APOE Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | apolipoprotein E (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | AD2 and LDLCQ5 and LPG, APOE and IDBG-56807 and ENSG00000130203 and 348, APOE and IDBG-639311 and ENSBTAG00000010123 and 281004, Apoe and IDBG-152108 and ENSMUSG00000002985 and 11816, cholinergic and biological process this GO :0007568 and aging and biological process this GO :0007603 and phototransduction, lipoprotein particle binding, nuclei, this GO :0000302 and response to reactive oxygen species and biological process this GO :0001523 and retinoid metabolic process and biological process this GO :0001540 and beta-amyloid binding and molecular function this GO :0001937 and negative regulation of endothelial cell proliferation and biological process this GO :0002021 and response to dietary excess and biological process this GO :0005102 and receptor binding and molecular function this GO :0005319 and lipid transporter activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005543 and phospholipid binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005634 and nucleus and cellular component this GO :0005635 and nuclear envelope and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005764 and lysosome and cellular component this GO :0005768 and endosome and cellular component this GO :0005769 and early endosome and cellular component this GO :0005770 and late endosome and cellular component this GO :0005783 and endoplasmic reticulum and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005874 and microtubule and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006629 and lipid metabolic process and biological process this GO :0006641 and triglyceride metabolic process and biological process this GO :0006707 and cholesterol catabolic process and biological process this GO :0006869 and lipid transport and biological process this GO :0006874 and cellular calcium ion homeostasis and biological process this GO :0006898 and receptor-mediated endocytosis and biological process this GO :0006979 and response to oxidative stress and biological process this GO :0007010 and cytoskeleton organization and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007263 and nitric oxide mediated signal transduction and biological process this GO :0007271 and synaptic transmission, this GO :0001540: beta-amyloid binding, this GO :0001540: beta-amyloid binding and also this GO :0005102: receptor binding and also this GO :0005319: lipid transporter activity and also this GO :0005515: protein binding and also this GO :0005543: phospholipid binding and also this GO :0008201: heparin binding and also this GO :0008289: lipid binding and also this GO :0016209: antioxidant activity and also this GO :0017127: cholesterol transporter activity and also this GO :0042802: identical protein binding and also this GO :0042803: protein homodimerization activity and also this GO :0046848: hydroxyapatite binding and also this GO :0046911: metal chelating activity and also this GO :0048156: tau protein binding and also this GO :0050750: low-density lipoprotein particle receptor binding and also this GO :0060228: phosphatidylcholine-sterol O-acyltransferase activator activity and also this GO :0070326: very-low-density lipoprotein particle receptor binding and also this GO :0071813: lipoprotein particle binding, this GO :0005102: receptor binding, this GO :0005319: lipid transporter activity, this GO :0005515: protein binding, this GO :0005543: phospholipid binding, this GO :0008201: heparin binding, this GO :0008289: lipid binding, this GO :0016209: antioxidant activity, this GO :0017127: cholesterol transporter activity, this GO :0042802: identical protein binding, this GO :0042803: protein homodimerization activity, this GO :0046848: hydroxyapatite binding, this GO :0046911: metal chelating activity, this GO :0048156: tau protein binding, this GO :0050750: low-density lipoprotein particle receptor binding, this GO :0060228: phosphatidylcholine-sterol O-acyltransferase activator activity, this GO :0070326: very-low-density lipoprotein particle receptor binding, this GO :0071813: lipoprotein particle binding, visible light and biological process this GO :0008201 and heparin binding and molecular function this GO :0008203 and cholesterol metabolic process and biological process this GO :0008219 and cell death and biological process this GO :0008289 and lipid binding and molecular function this GO :0009986 and cell surface and cellular component this GO :0010468 and regulation of gene expression and biological process this GO :0010544 and negative regulation of platelet activation and biological process this GO :0010873 and positive regulation of cholesterol esterification and biological process this GO :0010875 and positive regulation of cholesterol efflux and biological process this GO :0014012 and peripheral nervous system axon regeneration and biological process this GO :0015909 and long-chain fatty acid transport and biological process this GO :0016020 and membrane and cellular component this GO :0016209 and antioxidant activity and molecular function this GO :0017038 and protein import and biological process this GO :0017127 and cholesterol transporter activity and molecular function this GO :0019934 and cGMP-mediated signaling and biological process this GO :0030195 and negative regulation of blood coagulation and biological process this GO :0030425 and dendrite and cellular component this GO :0030516 and regulation of axon extension and biological process this GO :0030828 and positive regulation of cGMP biosynthetic process and biological process this GO :0031232 and extrinsic component of external side of plasma membrane and cellular component this GO :0032489 and regulation of Cdc42 protein signal transduction and biological process this GO :0032526 and response to retinoic acid and biological process this GO :0032805 and positive regulation of low-density lipoprotein particle receptor catabolic process and biological process this GO :0032868 and response to insulin and biological process this GO :0033344 and cholesterol efflux and biological process this GO :0033700 and phospholipid efflux and biological process this GO :0034361 and very-low-density lipoprotein particle and cellular component this GO :0034362 and low-density lipoprotein particle and cellular component this GO :0034363 and intermediate-density lipoprotein particle and cellular component this GO :0034364 and high-density lipoprotein particle and cellular component this GO :0034365 and discoidal high-density lipoprotein particle and cellular component this GO :0034372 and very-low-density lipoprotein particle remodeling and biological process this GO :0034374 and low-density lipoprotein particle remodeling and biological process this GO :0034375 and high-density lipoprotein particle remodeling and biological process this GO :0034380 and high-density lipoprotein particle assembly and biological process this GO :0034382 and chylomicron remnant clearance and biological process this GO :0034384 and high-density lipoprotein particle clearance and biological process this GO :0034447 and very-low-density lipoprotein particle clearance and biological process this GO :0042157 and lipoprotein metabolic process and biological process this GO :0042158 and lipoprotein biosynthetic process and biological process this GO :0042159 and lipoprotein catabolic process and biological process this GO :0042311 and vasodilation and biological process this GO :0042627 and chylomicron and cellular component this GO :0042632 and cholesterol homeostasis and biological process this GO :0042802 and identical protein binding and molecular function this GO :0042803 and protein homodimerization activity and molecular function this GO :0043025 and neuronal cell body and cellular component this GO :0043407 and negative regulation of MAP kinase activity and biological process this GO :0043524 and negative regulation of neuron apoptotic process and biological process this GO :0043537 and negative regulation of blood vessel endothelial cell migration and biological process this GO :0043691 and reverse cholesterol transport and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0045471 and response to ethanol and biological process this GO :0045541 and negative regulation of cholesterol biosynthetic process and biological process this GO :0045773 and positive regulation of axon extension and biological process this GO :0046848 and hydroxyapatite binding and molecular function this GO :0046889 and positive regulation of lipid biosynthetic process and biological process this GO :0046907 and intracellular transport and biological process this GO :0046911 and metal chelating activity and molecular function this GO :0048156 and tau protein binding and molecular function this GO :0048168 and regulation of neuronal synaptic plasticity and biological process this GO :0048709 and oli this GO dendrocyte differentiation and biological process this GO :0048844 and artery morphogenesis and biological process this GO :0050728 and negative regulation of inflammatory response and biological process this GO :0050750 and low-density lipoprotein particle receptor binding and molecular function this GO :0051000 and positive regulation of nitric-oxide synthase activity and biological process this GO :0051044 and positive regulation of membrane protein ectodomain proteolysis and biological process this GO :0051055 and negative regulation of lipid biosynthetic process and biological process this GO :0051651 and maintenance of location in cell and biological process this GO :0055088 and lipid homeostasis and biological process this GO :0055089 and fatty acid homeostasis and biological process this GO :0060228 and phosphatidylcholine-sterol O-acyltransferase activator activity and molecular function this GO :0060999 and positive regulation of dendritic spine development and biological process this GO :0061000 and negative regulation of dendritic spine development and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070326 and very-low-density lipoprotein particle receptor binding and molecular function this GO :0071347 and cellular response to interleukin-1 and biological process this GO :0071363 and cellular response to growth factor stimulus and biological process this GO :0071397 and cellular response to cholesterol and biological process this GO :0071682 and endocytic vesicle lumen and cellular component this GO :0071813 and lipoprotein particle binding and molecular function this GO :0072358 and cardiovascular system development and biological process this GO :0072562 and blood microparticle and cellular component this GO :0090370 and negative regulation of cholesterol efflux and biological process this GO :0097113 and alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering and biological process this GO :0097114 and N-methyl-D-aspartate receptor clustering and biological process this GO :1900221 and regulation of beta-amyloid clearance and biological process this GO :1901214 and regulation of neuron death and biological process this GO :1901215 and negative regulation of neuron death and biological process this GO :1901216 and positive regulation of neuron death and biological process this GO :1901627 and negative regulation of postsynaptic membrane organization and biological process this GO :1901628 and positive regulation of postsynaptic membrane organization and biological process this GO :1901630 and negative regulation of presynaptic membrane organization and biological process this GO :1901631 and positive regulation of presynaptic membrane organization and biological process this GO :1902004 and positive regulation of beta-amyloid formation and biological process this GO :1902430 and negative regulation of beta-amyloid formation and biological process this GO :1902947 and regulation of tau-protein kinase activity and biological process this GO :1902951 and negative regulation of dendritic spine maintenance and biological process this GO :1902952 and positive regulation of dendritic spine maintenance and biological process this GO :1902995 and positive regulation of phospholipid efflux and biological process this GO :1902998 and positive regulation of neurofibrillary tangle assembly and biological process this GO :1902999 and negative regulation of phospholipid efflux and biological process this GO :1903001 and negative regulation of lipid transport across blood brain barrier and biological process this GO :1903002 and positive regulation of lipid transport across blood brain barrier and biological process, apolipoprotein E |
| Identity | 613 |
| Gene | APOE |
| Long gene name | apolipoprotein E |
| Synonyms gene | AD2 |
| Synonyms gene name | Alzheimer disease 2 (APOE*E4-associated, late onset) |
| Locus | 19q13, 32 |
| Discovery year | 2001-06-22 |
| GenBank acession | K00396 |
| Entrez gene record | 348 |
| Pubmed identfication | 10662539 |
| RefSeq identity | NM_000041 |
| Classification | Apolipoproteins |
| Havana BLAST/BLAT | OTTHUMG00000128901 |
| Locus Specific Databases | ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database |
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