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Apolipoprotein B Antibody

Apolipoprotein B Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameApolipoprotein B Primary Polyclonal Antibody
Also known asApolipoprotein B PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenApoB
SpecificityThis is a highly specific antibody against ApoB
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range1540-1590/4563
Subcellular locationCytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Apolipoprotein B
Gene ID number338
Tested Applications IF(IHC-P), IHC-P
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen A disorder characterized by highly reduced plasma concentrations of low density lipoproteins, Apo B-100 functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor, Clinical presentation may vary from no symptoms to severe gastrointestinal and neurological dysfunction similar to abetalipoproteinemia, FDB is a dominantly inherited disorder of lipoprotein metabolism leading to hypercholesterolemia and increased proneness to coronary artery disease (CAD), LDL (apo B-100) and VLDL (apo B-100), The plasma cholesterol levels are dramatically elevated due to impaired clearance of LDL particles by defective APOB/E receptors, and dietary fat malabsorption, Apolipoprotein B is a major protein constituent of chylomicrons (apo B-48), Defects in APOB are a cause of familial ligand-defective apolipoprotein B-100 (FDB), Involvement in disease: Defects in APOB are a cause of hypobetalipoproteinemia familial type 1 (FHBL1)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names APOB protein, APOB_HUMAN, Apo B, Apo B-100, Apo B-48, ApoB, ApoB 100, ApoB 48, Apolipoprotein B, Apolipoprotein B 100, Apolipoprotein B 48, Apolipoprotein B-48, FLDB, Apo B 100
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetApolipoprotein B
Short nameApolipoprotein B Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameApolipoprotein B (Antibody to)
Alternative techniqueantibodies
Identity 603
Gene APOB
Long gene name apolipoprotein B
Synonyms gene name apolipoprotein B (including Ag(x) antigen)
Locus 2p24, 1
Discovery year 2001-06-22
GenBank acession M14162
Entrez gene record 338
Classification Apolipoproteins
Havana BLAST/BLAT OTTHUMG00000090785

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