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APPD Antibody

APPD Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameAPPD Primary Polyclonal Antibody
Also known asAPPD PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenAPPD
SpecificityThis is a highly specific antibody against APPD
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range75-125/279
Subcellular location Lysosome, Nucleus, Cytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human APPD/ Apoptosis-inducing protein
Gene ID number79156
Swiss ProtQ96S99
Tested ApplicationsIHC-P
Recommended dilutionsIHC-P(1:100-500)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Translocates to the lysosome initiating the permeabilization of lysosomal membrane (LMP) and resulting in the release of CTSD and CTSL to the cytoplasm, Triggers the caspase-independent apoptosis by altering mitochondrial membrane permeabilization (MMP) resulting in the release of PDCD8, May induce apoptosis through the lysosomal-mitochondrial pathway
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names Apoptosis-inducing protein, LAPF, Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains, PH and FYVE domain-containing protein 1, PH domain-containing family F member 1, PHAFIN1, PLEKHF1, Phafin-1, Pleckstrin homology domain-containing family F member 1, ZFYVE15, Zinc finger FYVE domain-containing protein 15, APPD
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetAPPD
Short nameAPPD Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameAPPD (Antibody to)
Alternative techniqueantibodies
Identity 20764
Gene PLEKHF1
Long gene name pleckstrin homology and FYVE domain containing 1
Synonyms gene name family F (with FYVE domain) member 1 , pleckstrin homology domain containing
Synonyms APPD MGC4090 PHAFIN1 ZFYVE15
Locus 19q12
Discovery year 2003-04-01
GenBank acession AF434818
Entrez gene record 79156
RefSeq identity NM_024310
Classification Pleckstrin homology domain containing Zinc fingers FYVE-type
Havana BLAST/BLAT OTTHUMG00000182097

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