Name : APRIL Antibody
Supplier : NJS POLY
Price :406
SKU : GEN2487940249
| Category | Antibody |
| Concentration | 2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | APRIL |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | ELISA, WB |
| Recommended dilutions | 1-0, 1-0, 5ug/ml, 5ug/ml, ELISA : 0, Western blot: 0 |
| Notes | Optimal dilution of the APRIL antibody should be determined by the researcher |
| Intented use | This APRIL antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | O75888 |
| Purity | Antigen affinity |
| Description | Alternative splicing results in multiple transcript variants, And this protein is a ligand for TNFRSF17/BCMA, In vitro experiments suggested that this protein may be able to induce apoptosis through its interaction with other TNF receptor family proteins such as TNFRSF6/FAS and TNFRSF14/HVEM, Some transcripts that skip the last exon of the upstream gene (TNFSF12) and continue into the second exon of this gene have been identified, TNFSF12-TNFSF13, The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family, This protein and its receptor are both found to be important for B cell development, a member of the TNF receptor family, also known as tumor necrosis factor ligand superfamily member 13 (TNFSF13), is a protein of the TNF superfamily recognized by the cell surface receptor TACI, such read-through transcripts are contained in GeneID 407977, A proliferation-inducing ligand (APRIL) |
| Immunogen | Amino acids PINATSKDDSDVTEVMWQPALRRGRGLQAQ of human APRIL were used as the immunogen for the APRIL antibody |
| Storage | Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the APRIL antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | APRIL |
| Short name | APRIL Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | APRIL (Antibody to) |
| Alternative technique | antibodies |
| Identity | 11928 |
| Gene | TNFSF13 |
| Long gene name | tumor necrosis factor superfamily member 13 |
| Synonyms gene name | member 13 , tumor necrosis factor (ligand) superfamily |
| Synonyms | APRIL CD256 |
| Locus | 17p13, 1 |
| Discovery year | 1998-12-04 |
| GenBank acession | AF046888 |
| Entrez gene record | 8741 |
| Pubmed identfication | 9743536 |
| RefSeq identity | NM_003808 |
| Classification | Tumor necrosis factor superfamily CD molecules |
| Havana BLAST/BLAT | OTTHUMG00000108145 |