| Long name | ARS2 Primary Polyclonal Antibody |
| Also known as | ARS2 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | ARS2 |
| Specificity | This is a highly specific antibody against ARS2 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ARS2 |
| Gene ID number | 51593 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | ASR1 shows almost complete homology with the rat fau gene, ASR1(Arsenite resistance protein 1) and ASR2 (Arsenite resistance protein 2), Arsenic is a human carcinogen whose mechanism of action is unknown, Arsenite inhibits ubiquitin dependent proteolysis, The arsenite acts as a comutagen by interfering with DNA repair, The protein belongs to the ARS2 family, The tumor suppressor fau gene product or some other aspect of the ubiquitin system may be a target for arsenic toxicity and that disruption of the ubiquitin system may contribute to the genotoxicity and carcinogenicity of arsenite, Two genes, a tumor suppressor gene which contains a ubiquitin like region fused to S30 ribosomal protein, confer arsenite resistance to arsenite-sensitive cells, ARS2(Arsenite resistance protein 2) confers arsenite resistance |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | ASR2, Arsenate resistance protein ARS2, Arsenite resistance protein, Arsenite resistance protein 2, MGC126427, SRRT, SRRT_HUMAN, Serrate, Serrate RNA effector molecule homolog, Serrate RNA effector molecule homolog Arabidopsis, ARS2 protein |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | ARS2 |
| Short name | ARS2 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | ARS2 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 24101 |
| Gene | SRRT |
| Long gene name | RNA effector molecule , serrate |
| Synonyms gene name | serrate RNA effector molecule homolog (Arabidopsis) |
| Synonyms | Asr2 serrate ARS2 |
| Synonyms name | arsenite resistance protein |
| Locus | 7q22, 1 |
| Discovery year | 2009-03-02 |
| Entrez gene record | 51593 |
| Pubmed identfication | 11239002 11230166 |
| RefSeq identity | NM_015908 |
| Havana BLAST/BLAT | OTTHUMG00000157031 |