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ATF2 Antibody, Cy7 Conjugated

ATF2 Antibody, Cy7 Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy7 Conjugated, ATF2 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationCy7
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenATF2
SpecificityThis is a highly specific antibody against ATF2
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range415-455/505
Subcellular location Mitochondrion, Nucleus, Cytoplasm
SourceKLH conjugated synthetic peptide derived from human ATF2
Gene ID number1386
Swiss ProtP15336
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Can elicit oncogenic or tumor suppressor activities depending on the tissue or cell type, Dependent on its binding partner, Exhibits histone acetyltransferase (HAT) activity which specifically acetylates histones H2B and H4 in vitro, In concert with CUL3 and RBX1, In the cytoplasm, In the nucleus, The phosphorylated form (mediated by ATM) plays a role in the DNA damage response and is involved in the ionizing radiation (IR)-induced S phase checkpoint control and in the recruitment of the MRN complex into the IR-induced foci (IRIF), and DNA damage response, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA-3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA-3'), cell growth, contributes to global transcription and the DNA damage response, in addition to specific transcriptional activities that are related to cell development, including those involved in anti-apoptosis, inducing mitochondrial leakage and promoting cell death, interacts with and perturbs HK1- and VDAC1-containing complexes at the mitochondrial outer membrane, proliferation and death, promotes the degradation of KAT5 thereby attenuating its ability to acetylate and activate ATM, thereby impairing mitochondrial membrane potential, Transcriptional activator which regulates the transcription of various genes
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission743nm/767nm
Synonyms ATF1 ATF2 HFB1-GDNF
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
ConjugatedThese antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths
Gene targetATF2 Conjugated
Short name Conjugated, ATF2 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy7
Alternative name cyanine 7 coupled, ATF2 (Antibody to)
Alternative techniqueantibodies
Identity 4232
Gene GDNF
Long gene name glial cell derived neurotrophic factor
Synonyms name astrocyte-derived trophic factor glial cell line derived neurotrophic factor glial derived neurotrophic factor
Locus 5p13, 2
Discovery year 1995-05-04
Entrez gene record 2668
Pubmed identfication 8493557
RefSeq identity NM_000514
Classification Endogenous ligands
Havana BLAST/BLAT OTTHUMG00000090809

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