ATG1/ULK1 Antibody, Biotin Conjugated

ATG1/ULK1 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1

Price 333

Size 0.1ml

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Long name	Biotin Conjugated, ATG1/ULK1 Polyclonal Antibody
Category	Conjugated Primary Antibodies
Conjugation	Biotinylated
Host Organism	Rabbit (Oryctolagus cuniculus)
Target Antigen	ATG1/ULK1
Specificity	This is a highly specific antibody against ATG1/ULK1
Modification	Unmodified
Modification site	None
Clonality	Polyclonal
Clone	Polyclonal antibody
Concentration	1ug per 1ul
Immunogen_range	1004-1050/1050
Subcellular location	Cytoplasm
Source	KLH conjugated synthetic peptide derived from human ATG1/ULK1
Gene ID number	8408
Swiss Prot	O75385
Tested applications	IHC-P, WB
Recommended dilutions	IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity	Mouse, Rat, Human
Crossreactive species details	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background	Activated via phosphorylation by AMPK and also acts as a regulator of AMPK by mediating phosphorylation of AMPK subunits PRKAA1, Acts upstream of phosphatidylinositol 3-kinase PIK3C3 to regulate the formation of autophagophores, May phosphorylate ATG13/KIAA652 and RPTOR, PRKAB2 and PRKAG1, Part of regulatory feedback loops in autophagy: acts both as a downstream effector and negative regulator of mammalian target of rapamycin complex 1 (mTORC1) via interaction with RPTOR, Plays a role early in neuronal differentiation and is required for granule cell axon formation, however such data need additional evidences, leading to negatively regulate AMPK activity, the precursors of autophagosomes, Serine/threonine-protein kinase involved in autophagy in response to starvation
Purification method	This antibody was purified via Protein A
Storage conditions	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission	N/A
Synonyms	ATG1 ATG1A
Properties	Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target	ATG1/ULK1 Conjugated
Short name	Conjugated, ATG1/ULK1 Antibody
Technique	antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label	Biotin
Alternative name	biotinilated coupled, ATG1/ULK1 (Antibody to)
Alternative technique	antibodies
Identity	12558
Gene	ULK1
Long gene name	unc-51 like autophagy activating kinase 1
Synonyms gene name	elegans) , elegans)-like kinase 1 unc-51-like kinase 1 (C, unc-51 (C
Synonyms name	ATG1 autophagy related 1 homolog (S, cerevisiae)
Locus	12q24, 33
Discovery year	1998-09-03
GenBank acession	AF045458
Entrez gene record	8408
Pubmed identfication	9693035
Classification	Autophagy related
Havana BLAST/BLAT	OTTHUMG00000168052

ATG1/ULK1 Antibody, Biotin Conjugated

ATG1/ULK1 Antibody, Biotin Conjugated size: 0.1ml 333

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