| Alternative name1 | AIP4, ITCH, Itchy Homolog E3 Ubiquitin Protein Ligase (mouse), NAPP1, NFE2-associated Polypeptide 1, dJ468O1, dJ468O1, 1, 1), Anti-Atrophin-1 Interacting Protein 4 (AIF4 |
| Alternative name2 | AIP4, ITCH, Itchy Homolog E3 Ubiquitin Protein Ligase (Murine), NAPP1, NFE2-associated Polypeptide 1, dJ468O1, dJ468O1, 1, 1), Atrophin-1 Interacting Protein 4 (AIF4 |
| Alternative name3 | AIP4, ITCH, Itchy Homolog E3 Ubiquitin Protein Ligase (Mus musculus), NAPP1, NFE2-associated Polypeptide 1, dJ468O1, dJ468O1, 1, 1), Atrophin-1 Interacting Protein 4 (AIF4 |
| Alternative name4 | Atrophin-1 Interacting Protein 4 |
| Alternative name5 | AIP4, ITCH, Itchy Homolog E3 Ubiquitin Protein Ligase (mouse), NAPP1, NFE2-associated Polypeptide 1, dJ468O1, dJ468O1, 1, 1), Anti -Atrophin-1 Interacting Protein 4 (AIF4 |
| Other names | E3 ubiquitin-protein ligase Itchy homolog, Itchy homolog E3 ubiquitin protein ligase variant, N/A, NFE2-associated polypeptide 1, OTTHUMP00000030688, OTTHUMP00000030689, atrophin-1 interacting protein 4, atrophin-1-interacting protein 4, dJ468O1, itchy E3 ubiquitin protein ligase homolog (mouse), itchy homolog E3 ubiquitin protein ligase, ubiquitin protein ligase ITCH, 1 (atrophin 1 interacting protein 4 (AIP4)), atrophin-1 interacting protein 4 |
| Gene name | N/A |
| Gene name synonims | N/A |
| Other gene names | AIF4, AIP4, N/A, N/A, NAPP1, dJ468O1, 1, ITCH |
| Category | Antibodies |
| Clonality | Polyclonal |
| Immunoglobulin isotype | N/A |
| Clone | Polyclonal antibody |
| Host organism | Source: Human, Host: Goat |
| Species reactivity | Human, Mouse, Rat, Canine |
| Specificity and cross-reactivity | Species Crossreactivity: Canine, mouse and rat, 3), 7kD according to NP_113671, Recognizes human AIF4 at ~100kDa band observed in Human Brain (Frontal Cortex) lysates (calculated MW of 98 |
| Purification method | Affinity Purified by immunoaffinity chromatography |
| Form/Appearance | 0, 0, pH 7, 02% sodium azide, 2, 5% BSA, Supplied as a liquid in Tris-saline |
| Concentration | N/A |
| Storage and shipping | Aliquots are stable for at least 12 months productone should be stored at -20 degrees Celsius, For long-term storage and to avoid repeated freezing and thawing, For maximum recovery of product, Further dilutions can be made in assay buffer, aliquot and For optimal long term storage, centrifuge the original vial after thawing and prior to removing the cap, productone should be kept at -20 degrees Celsius, Store at 4 degrees Celsius for short term storage |
| Tested for: | Western Blot (WB), ELISA (EL/EIA) |
| Description | Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target | ITCH, Itchy Homolog E3 Ubiquitin Protein Ligase AIP4, NAPP1, NFE2-associated Polypeptide 1, dJ468O1, dJ468O1, 1, 1), Atrophin-1 Interacting Protein 4 (AIF4 |
| Short name | ITCH, Itchy Homolog E3 Ubiquitin Protein Ligase (mouse) AIP4, NAPP1, NFE2-associated Polypeptide 1, dJ468O1, dJ468O1, 1, 1) Antibody, Atrophin-1 Interacting Protein 4 (AIF4 |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Host | mouse |
| Alternative name | 45kDa-associated multipeptide 1, AIP4, Itchy Homolog E3 Ubiquitin Protein Ligase (mouse), NAPP1, dJ468O1, dJ468O1, itchy E3 ubiquitin protein ligase, nuclear factor (erythroid-derived 2), 1, 1) (Antibody to), Atrophin-1 Interacting Protein 4 (AIF4 |
| Alternative technique | antibodies |
| Alternative to gene target | 45kDa, CXCR chemokine receptor binding, DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006357 and regulation of transcription from RNA polymerase II promoter and biological process this GO :0007267 and cell-cell signaling and biological process this GO :0007275 and multicellular organismal development and biological process this GO :0007596 and blood coagulation and biological process this GO :0007599 and hemostasis and biological process this GO :0008015 and blood circulation and biological process this GO :0015629 and actin cytoskeleton and cellular component this GO :0016605 and PML body and cellular component this GO :0030502 and negative regulation of bone mineralization and biological process this GO :0034242 and negative regulation of syncytium formation by plasma membrane fusion and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0047485 and protein N-terminus binding and molecular function this GO :0050699 and WW domain binding and molecular function this GO :0060716 and labyrinthine layer blood vessel development and biological process this GO :2000758 and positive regulation of peptidyl-lysine acetylation and biological process, ITCH and IDBG-641890 and ENSBTAG00000000308 and 508431, ITCH and IDBG-68143 and ENSG00000078747 and 83737, Itch and IDBG-210517 and ENSMUSG00000027598 and 16396, NF-E2 and p45, NFE2 and IDBG-37778 and ENSG00000123405 and 4778, NFE2 and IDBG-631149 and ENSBTAG00000001562 and 514006, Nfe2 and IDBG-189502 and ENSMUSG00000058794 and 18022, WW domain binding, itchy E3 ubiquitin protein ligase, leucine rich repeat containing receptor signaling pathway and biological process this GO :0042787 and protein ubiquitination involved in ubiquitin-dependent protein catabolic process and biological process this GO :0043021 and ribonucleoprotein complex binding and molecular function this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045236 and CXCR chemokine receptor binding and molecular function this GO :0045732 and positive regulation of protein catabolic process and biological process this GO :0046329 and negative regulation of JNK cascade and biological process this GO :0046642 and negative regulation of alpha-beta T cell proliferation and biological process this GO :0046718 and viral entry into host cell and biological process this GO :0050687 and negative regulation of defense response to virus and biological process this GO :0051607 and defense response to virus and biological process this GO :0070423 and nucleotide-binding oli this GO merization domain containing signaling pathway and biological process this GO :0070534 and protein K63-linked ubiquitination and biological process this GO :0070936 and protein K48-linked ubiquitination and biological process this GO :0090085 and regulation of protein deubiquitination and biological process, nuclei, nuclei, this GO :0000209 and protein polyubiquitination and biological process this GO :0001558 and regulation of cell growth and biological process this GO :0002669 and positive regulation of T cell anergy and biological process this GO :0004842 and ubiquitin-protein transferase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005938 and cell cortex and cellular component this GO :0006511 and ubiquitin-dependent protein catabolic process and biological process this GO :0006915 and apoptotic process and biological process this GO :0006954 and inflammatory response and biological process this GO :0007219 and Notch signaling pathway and biological process this GO :0016020 and membrane and cellular component this GO :0016567 and protein ubiquitination and biological process this GO :0016874 and ligase activity and molecular function this GO :0031410 and cytoplasmic vesicle and cellular component this GO :0032088 and negative regulation of NF-kappaB transcription factor activity and biological process this GO :0032480 and negative regulation of type I interferon production and biological process this GO :0035519 and protein K29-linked ubiquitination and biological process this GO :0035872 and nucleotide-binding domain, this GO :0003677 and DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0003713 and transcription coactivator activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006337 and nucleosome disassembly and biological process this GO :0006351 and transcription, this GO :0003677: DNA binding, this GO :0003677: DNA binding and also this GO :0003700: sequence-specific DNA binding transcription factor activity and also this GO :0003713: transcription coactivator activity and also this GO :0005515: protein binding and also this GO :0043565: sequence-specific DNA binding and also this GO :0047485: protein N-terminus binding and also this GO :0050699: WW domain binding, this GO :0003700: sequence-specific DNA binding transcription factor activity, this GO :0003713: transcription coactivator activity, this GO :0004842: ubiquitin-protein transferase activity, this GO :0004842: ubiquitin-protein transferase activity and also this GO :0005515: protein binding and also this GO :0016874: ligase activity and also this GO :0043021: ribonucleoprotein complex binding and also this GO :0045236: CXCR chemokine receptor binding, this GO :0005515: protein binding, this GO :0005515: protein binding, this GO :0016874: ligase activity, this GO :0043021: ribonucleoprotein complex binding, this GO :0043565: sequence-specific DNA binding, this GO :0045236: CXCR chemokine receptor binding, this GO :0047485: protein N-terminus binding, this GO :0050699: WW domain binding, nuclear factor (erythroid-derived 2) |
| Identity | 7780 |
| Gene | NFE2 |
| Long gene name | erythroid 2 , nuclear factor |
| Synonyms gene name | 45kD nuclear factor (erythroid-derived 2), 45kDa , nuclear factor (erythroid-derived 2) |
| Synonyms | NF-E2 |
| Locus | 12q13 |
| Discovery year | 1993-11-03 |
| GenBank acession | BC005044 |
| Entrez gene record | 4778 |
| Pubmed identfication | 8355703 |
| RefSeq identity | NM_006163 |
| Classification | Basic leucine zipper proteins |
| Havana BLAST/BLAT | OTTHUMG00000169761 |
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