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ATXN1 (Ser775) Antibody, Biotin Conjugated

ATXN1 (Ser775) Antibody, Biotin Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, ATXN1 (Ser775) Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenATXN1 Ser775
SpecificityThis is a highly specific antibody against ATXN1 Ser775
ModificationPhosphorylation
Modification siteSer775
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human Ataxin-1 around the phosphorylation site of Ser775
Gene ID number6310
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background 2, 3, 4 and 6, ADCA has been divided into three groups: ADCA types I-III, ADCA is caused by the expansion of the CAG repeats, ADCAI is genetically heterogeneous, ADCAII, At least two transcript variants encoding the same protein have been found for this gene, Clinically, Several SCA genes have been cloned and shown to contain CAG repeats in their coding regions, The expanded repeats are variable in size and unstable, The function of the ataxins is not known, This locus has been mapped to chromosome 6, [provided by RefSeq], and ADCAIII often referred to as the `pure' cerebellar syndrome (SCA5), and is associated with spinocerebellar ataxia type 1 (SCA1), and it has been determined that the diseased allele contains41-81 CAG repeats, are most likely homogeneous disorders, being assigned to five different chromosomes, brain stem and spinal cord, compared to 6-39 in the normal allele, designated spinocerebellar ataxia (SCA) 1, producing an elongated polyglutamine tract in the corresponding protein, usually increasing in size when transmitted to successive generations, which always presents with retinal degeneration (SCA7), with five genetic loci, The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms D6S504E ATX1
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetATXN1 (Ser775) Conjugated
Short name Conjugated, ATXN1 (Ser775) Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, ATXN1 (Ser775) (Antibody to)
Alternative techniqueantibodies
Identity 10548
Gene ATXN1
Long gene name ataxin 1
Synonyms gene SCA1
Synonyms gene name ataxin 1) , autosomal dominant, spinocerebellar ataxia 1 (olivopontocerebellar ataxia 1
Locus 6p22, 3
Discovery year 1986-01-01
GenBank acession X79204
Entrez gene record 6310
Pubmed identfication 1582256
RefSeq identity NM_000332
Classification Ataxins
Havana BLAST/BLAT OTTHUMG00000014303
Locus Specific Databases LRG_863

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