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Aurka Antibody

Aurka Antibody size: 0.4 ml 406

Supplier NJS POLY
Price 406
Size 0.4 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenAurka
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Mouse (Mus musculus)
Tested applications ELISA, WB
Recommended dilutionsWestern blot: 1:1000
NotesTitration of the Aurka antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis Aurka antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P97477
PurityAntigen affinity
Description Associates with the centrosome and the spindle microtubules during mitosis and functions in centrosome maturation, BRCA1, Important for microtubule formation and/or stabilization, KIF2A, NDEL1, PARD3, PLK1 and BORA, Phosphorylates numerous target proteins, Plays a role in microtubule remodeling during neurite extension, Regulates KIF2A tubulin depolymerase activity (By similarity), Required for normal axon formation, Required for normal mitosis, centrosome separation and mitotic checkpoint control, including ARHGEF2, maintenance of spindle bipolarity, spindle assembly, Contributes to the regulation of cell cycle progression
ImmunogenA portion of amino acids 93-120 from the mouse protein was used as the immunogen for this Aurka antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the Aurka antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetAurka
Short nameAurka Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameAurka (Antibody to)
Alternative techniqueantibodies
Identity 11393
Gene AURKA
Long gene name aurora kinase A
Synonyms gene STK15 STK6
Synonyms gene name serine/threonine kinase 15 serine/threonine kinase 6
Synonyms BTAK AurA STK7 ARK1 PPP1R47 AIK
Synonyms name protein phosphatase 1, regulatory subunit 47 Aurora-A kinase
Locus 20q13, 2
Discovery year 1998-10-02
GenBank acession BC001280
Entrez gene record 6790
Pubmed identfication 9174055 9771714
RefSeq identity NM_003600
Classification Protein phosphatase 1 regulatory subunits
Havana BLAST/BLAT OTTHUMG00000032796

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