Name : B-Raf (Thr401) Antibody, Cy3 Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :368
SKU : GEN3706571280
| Long name | Cy3 Conjugated, B-Raf (Thr401) Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | cy3 conjugation kit |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | B-Raf Thr401 |
| Specificity | This is a highly specific antibody against B-Raf Thr401 |
| Modification | Phosphorylation |
| Modification site | Thr401 |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic phosphopeptide derived from human B-Raf around the phosphorylation site of Thr401 |
| Gene ID number | 673 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | 1 BRAF is important for the regulation of cell proliferation and determination of cell fate during embryogenesis, B-Raf is a serine/threonine protein kinase that acts as a signal transducer from membrane-associated receptors to nuclear transcription factors, BRAF acts downstream of Ras and upstream of MEK in the Ras-Raf-MEK-ERK signal transduction pathway, Defects in BRAF are involved in a wide range of cancers, Interaction between Ras proteins and Raf proteins results in Raf-mediated phosphorylation and activation of MEK (also known as MAP kinase kinase), Raf protein family members, and differentiation in response to growth factors, and hormones, cytokines, have intrinsic serine/threonine kinase activity, including A Raf and B Raf, proliferation, which is a conserved RAS-activated protein kinase cascade that regulates cell growth, The Raf kinases are important intermediates in signal transduction |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 512, 550nm/570, 615nm |
| Synonyms | 94 kDa B raf protein, B Raf proto oncogene serine threonine protein kinase, B raf 1, BRAF 1, BRAF1, BRAF_HUMAN, Braf, FLJ95109, MGC126806, MGC138284, Murine sarcoma viral v raf oncogene homolog B1, Murine sarcoma viral v-raf oncogene homolog B1, RAFB 1, RAFB1, cRmil, p-B Raf phospho T401, p94, v raf murine sarcoma viral oncogene homolog B1, B Raf phospho T401 |
| Properties | 1 of the B-Raf (Thr401) Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | B-Raf (Thr401) Conjugated |
| Short name | Conjugated, B-Raf (Thr401) Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Cy3 |
| Alternative name | cyanine 3 coupled, B-Raf (Thr401) (Antibody to) |
| Alternative technique | antibodies |