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BACE Antibody

BACE Antibody size: 0.4 ml 406

Supplier NJS POLY
Price 406
Size 0.4 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormPurified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenBACE
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, WB
Recommended dilutionsWestern blot: 1:1000
NotesTitration of the BACE antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis BACE antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P56817
PurityPurified
Description Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, This protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi, one of which is BACE, Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease
ImmunogenA portion of amino acids 476-501 from the human protein was used as the immunogen for this BACE antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the BACE antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetBACE
Short nameBACE Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameBACE (Antibody to)
Alternative techniqueantibodies
Identity 933
Gene BACE1
Long gene name beta-secretase 1
Synonyms gene BACE
Synonyms gene name beta-site APP-cleaving enzyme beta-site APP-cleaving enzyme 1
Locus 11q23, 3
Discovery year 1999-10-29
GenBank acession AF190725
Entrez gene record 23621
Pubmed identfication 10531052
Havana BLAST/BLAT OTTHUMG00000160636

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