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BACE1 (Ser498) Antibody, FITC Conjugated

BACE1 (Ser498) Antibody, FITC Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, BACE1 (Ser498) Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenBACE1 Ser498
SpecificityThis is a highly specific antibody against BACE1 Ser498
ModificationPhosphorylation
Modification siteSer498
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human BACE1 around the phosphorylation site of Ser498
Gene ID number23621
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein(APP) by two proteases, Multiple transcript variants encoding different isoforms have been described for this gene, The encoded protein, [provided by RefSeq], a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi, one of which is the protein encoded by this gene, Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetBACE1 (Ser498) Conjugated
Short name FITC Conjugated, BACE1 (Ser498) Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, BACE1 (Ser498) (Antibody to)
Alternative techniqueantibodies
Identity 933
Gene BACE1
Long gene name beta-secretase 1
Synonyms gene BACE
Synonyms gene name beta-site APP-cleaving enzyme beta-site APP-cleaving enzyme 1
Locus 11q23, 3
Discovery year 1999-10-29
GenBank acession AF190725
Entrez gene record 23621
Pubmed identfication 10531052
Havana BLAST/BLAT OTTHUMG00000160636

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