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BBS2 Antibody, ALEXA FLUOR 488

BBS2 Antibody, ALEXA FLUOR 488 size: 100ul 332

Price 332
Size 100ul
Long name ALEXA FLUOR 488 Conjugated, BBS2 Polyclonal Antibody
Also known asAnti-BBS2 PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated with 488, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenBBS2
SpecificityThis is a highly specific antibody against BBS2
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human BBS2
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen BBS is a heterogeneous disorder that maps to eight genetic loci and encodes eight proteins, BBS1-BBS8, BBS2 is a 721-amino acid protein that is evolutionarily conserved and is expressed in a broad range of tissues including: brain, BBS2 retinopathy involves normal retina development followed by apoptotic death of photoreceptors, Five BBS genes encode basal body or cilia proteins, Loss of BBS2 may be involved in defects in social interactions as well as infertility, Other associated clinical findings in BBS patients include diabetes, adrenal gland, and congenital heart defects, and developmental delay, and thyroid gland, hypertension, hypogenitalism, kidney, photoreceptor degeneration, polydactyly, renal abnormalities, suggesting that BBS is a ciliary dysfunction disorder, the primary ciliated cells of the retina, Bardet-Biedl syndrome (BBS) is a pleiotropic genetic disorder characterized by obesity
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission499nm/519nm
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the BBS2 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetBBS2
Short nameBBS2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 488
Alternative name ALEXA FLUOR 488, Bardet-Biedl syndrome 2 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target BBS, BBS2 and IDBG-32014 and ENSG00000125124 and 102724038, BT, Bbs2 and IDBG-181517 and ENSMUSG00000031755 and 67378, Cytoplasm, protein binding, this GO :0001103 and RNA polymerase II repressing transcription factor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0007288 and sperm axoneme assembly and biological process this GO :0007601 and visual perception and biological process this GO :0008104 and protein localization and biological process this GO :0010629 and negative regulation of gene expression and biological process this GO :0014824 and artery smooth muscle contraction and biological process this GO :0021756 and striatum development and biological process this GO :0021766 and hippocampus development and biological process this GO :0021987 and cerebral cortex development and biological process this GO :0030534 and adult behavior and biological process this GO :0031514 and motile cilium and cellular component this GO :0032402 and melanosome transport and biological process this GO :0033210 and leptin-mediated signaling pathway and biological process this GO :0033365 and protein localization to organelle and biological process this GO :0034464 and BBSome and cellular component this GO :0035058 and nonmotile primary cilium assembly and biological process this GO :0036064 and ciliary basal body and cellular component this GO :0038108 and negative regulation of appetite by leptin-mediated signaling pathway and biological process this GO :0040015 and negative regulation of multicellular organism growth and biological process this GO :0040018 and positive regulation of multicellular organism growth and biological process this GO :0042311 and vasodilation and biological process this GO :0042384 and cilium assembly and biological process this GO :0043001 and this GO lgi to plasma membrane protein transport and biological process this GO :0044321 and response to leptin and biological process this GO :0045444 and fat cell differentiation and biological process this GO :0045494 and photoreceptor cell maintenance and biological process this GO :0048854 and brain morphogenesis and biological process this GO :0051216 and cartilage development and biological process this GO :0060170 and ciliary membrane and cellular component this GO :0060271 and cilium morphogenesis and biological process this GO :0060296 and regulation of cilium beat frequency involved in ciliary motility and biological process, this GO :0001103: RNA polymerase II repressing transcription factor binding, this GO :0001103: RNA polymerase II repressing transcription factor binding and also this GO :0005515: protein binding, this GO :0005515: protein binding, 41087 and IDBG-632026 and ENSBTAG00000014923 and 533611, 583, Bardet-Biedl syndrome 2
Identity 967
Gene BBS2
Long gene name Bardet-Biedl syndrome 2
Synonyms gene BBS
Locus 16q13
Discovery year 1993-10-26
GenBank acession AF342736
Entrez gene record 583
Pubmed identfication 11285252
RefSeq identity NM_031885
Classification Bardet-Biedl syndrome associated BBSome
Havana BLAST/BLAT OTTHUMG00000176943
Locus Specific Databases Mutations of the Bardet-Biedl Syndrome Type 2 Gene

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