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Beclin Antibody

Beclin Antibody size: 0.4 ml 406

Supplier NJS POLY
Price 406
Size 0.4 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormPurified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenBeclin
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, IHC, WB, FACS
Recommended dilutionsFlow Cytometry: 1:10-1:50, IHC (Paraffin): 1:50-1:100, Western blot: 1:1000
NotesTitration of the Beclin antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis Beclin antibodyis to be used only for research purposes and not for diagnostics
Uniprot #Q14457
PurityPurified
Description Beclin 1 is thought to function as a VPS and autophagy protein as part of a complex with Class III PI3 kinase, Beclin 1 plays a role in two fundamentally important cell biological pathways: autophagy and apoptosis, Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, Vps34, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole), Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells
ImmunogenA portion of amino acids 210-239 from the human protein was used as the immunogen for this Beclin antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the Beclin antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetBeclin
Short nameBeclin Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameBeclin (Antibody to)
Alternative techniqueantibodies
Identity 51330
Gene BECN1P2
Long gene name beclin 1 pseudogene 2
Synonyms gene name autophagy related, beclin 1, pseudogene 2
Locus 6q13
Discovery year 2014-10-03
Entrez gene record 100420149
RefSeq identity NG_025950
Havana BLAST/BLAT OTTHUMG00000014998

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