Name : BMP1 Antibody
Supplier : NJS POLY
Price :199
SKU : GEN7231529812
| Category | Antibody |
| Concentration | pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form | Purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | BMP1 |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Mouse (Mus musculus) |
| Tested applications | ELISA, WB, IHC |
| Recommended dilutions | IHC (Paraffin): 1:50-1:100, Western blot: 1:1000 |
| Notes | Titration of the BMP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use | This BMP1 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | P13497 |
| Purity | Purified |
| Description | Although other bone morphogenetic proteins are members of the TGF-beta superfamily, BMP1 encodes a protein that is not closely related to other known growth factors, BMP1 protein and procollagen C proteinase (PCP), II, PCP or BMP1 protein cleaves the C-terminal propeptides of procollagen I, The BMP1 gene is expressed as alternatively spliced variants that share an N-terminal protease domain but differ in their C-terminal region, a secreted metalloprotease requiring calcium and needed for cartilage and bone formation, and III and its activity is increased by the procollagen C-endopeptidase enhancer protein, are identical, The BMP1 locus encodes a protein that is capable of inducing formation of cartilage in vivo |
| Immunogen | A portion of amino acids 957-986 from the human protein was used as the immunogen for this BMP1 antibody |
| Storage | Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the BMP1 antibody and store frozen at -20 deg |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | BMP1 |
| Short name | BMP1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | bone morphogenetic protein 1 (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | BMP1 and IDBG-10398 and ENSG00000168487 and 649, BMP1 and IDBG-634694 and ENSBTAG00000000917 and, Bmp1 and IDBG-178672 and ENSMUSG00000022098 and 12153, Extracellular, OI13 and PCOLC and PCP and PCP2 and TLD, this GO :0001501 and skeletal system development and biological process this GO :0001502 and cartilage condensation and biological process this GO :0001503 and ossification and biological process this GO :0004222 and metalloendopeptidase activity and molecular function this GO :0005125 and cytokine activity and molecular function this GO :0005509 and calcium ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005578 and proteinaceous extracellular matrix and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0006508 and proteolysis and biological process this GO :0007275 and multicellular organismal development and biological process this GO :0008083 and growth factor activity and molecular function this GO :0008233 and peptidase activity and molecular function this GO :0008237 and metallopeptidase activity and molecular function this GO :0008270 and zinc ion binding and molecular function this GO :0022617 and extracellular matrix disassembly and biological process this GO :0030154 and cell differentiation and biological process this GO :0030198 and extracellular matrix organization and biological process this GO :0031988 and membrane-bounded vesicle and cellular component this GO :0042157 and lipoprotein metabolic process and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0061036 and positive regulation of cartilage development and biological process, this GO :0004222: metalloendopeptidase activity, this GO :0004222: metalloendopeptidase activity and also this GO :0005125: cytokine activity and also this GO :0005509: calcium ion binding and also this GO :0005515: protein binding and also this GO :0008083: growth factor activity and also this GO :0008233: peptidase activity and also this GO :0008237: metallopeptidase activity and also this GO :0008270: zinc ion binding, this GO :0005125: cytokine activity, this GO :0005509: calcium ion binding, this GO :0005515: protein binding, this GO :0008083: growth factor activity, this GO :0008233: peptidase activity, this GO :0008237: metallopeptidase activity, this GO :0008270: zinc ion binding, zinc ion binding, bone morphogenetic protein 1 |
| Identity | 1067 |
| Gene | BMP1 |
| Long gene name | bone morphogenetic protein 1 |
| Synonyms gene | PCOLC |
| Synonyms gene name | procollagen C-endopeptidase |
| Synonyms name | procollagen C-endopeptidase |
| Locus | 8p21, 3 |
| Discovery year | 1990-06-11 |
| Entrez gene record | 649 |
| Pubmed identfication | 2004778 |
| RefSeq identity | NM_006132 |
| Classification | Bone morphogenetic proteins Astacins |
| Havana BLAST/BLAT | OTTHUMG00000097761 |