Name : BOP1 Antibody, Cy7 Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :350
SKU : GEN9316030377
| Long name | Cy7 Conjugated, BOP1 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Cy7 |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | BOP1 |
| Specificity | This is a highly specific antibody against BOP1 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human BOP1 |
| Gene ID number | 23246 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | BOP1 (Block of proliferation 1 protein) is a 746 amino acid highly conserved non-ribosomal protein that is involved in ribosome biogenesis, BOP1 physically interacts with pescadillo (a protein involved in cell proliferation) and enables efficient incorporation of pescadillo into the nucleolar preribosomal complexes, Deregulation of BOP1 may lead to colorectal tumorigenesis, The BOP1-pescadillo complex is also necessary for biogenesis of 60S ribosomal subunits, This suggests that BOP1 is involved in the formation of mature rRNAs and in the biogenesis of the 60S ribosomal subunit, Truncation of the amino terminus of BOP1 leads to cell growth arrest in the G1 phase and specific inhibition of 28S and 5, as well as a deficit in the cytosolic 60S ribosomal subunit, thereby affecting rRNA maturation and the cell cycle, 8S rRNA synthesis, Predominantly localized to the nucleolus |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 743nm/767nm |
| Synonyms | KIAA0124 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated | These antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths |
| Gene target | BOP1 Conjugated |
| Short name | Conjugated, BOP1 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Cy7 |
| Alternative name | cyanine 7 coupled, BOP1 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 15519 |
| Gene | BOP1 |
| Long gene name | block of proliferation 1 |
| Locus | 8q24, 3 |
| Discovery year | 2001-08-28 |
| GenBank acession | AK024840 |
| Entrez gene record | 23246 |
| Pubmed identfication | 8590280 |
| RefSeq identity | NM_015201 |
| Classification | WD repeat domain containing |
| Havana BLAST/BLAT | OTTHUMG00000174603 |