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BRD8 Antibody

BRD8 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameBRD8 Primary Polyclonal Antibody
Also known asBRD8 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenBRD8
SpecificityThis is a highly specific antibody against BRD8
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range340-410/1235
Subcellular locationNucleus
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human BRD8
Gene ID number10902
Swiss ProtQ9H0E9
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen At least isoform 1 and isoform 2 are components of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A, Component of a SWR1-like complex that specifically mediates the removal of histone H2A, ESR1/NR3A1, Isoform 2 stimulates transcriptional activation by AR/DHTR, NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage, RXRA/NR2B1 and THRB/ERBA2, This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription, and DNA repair, apoptosis, tumor suppressor mediated growth arrest and replicative senescence, May act as a coactivator during transcriptional activation by hormone-activated nuclear receptors (NR), Z/H2AFZ from the nucleosome
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names BRD8, Bromodomain-containing protein 8, SMAP2, Skeletal muscle abundant protein, Skeletal muscle abundant protein 2, Thyroid hormone receptor coactivating protein of 120 kDa, TrCP120, p120, SMAP
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetBRD8
Short nameBRD8 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameBRD8 (Antibody to)
Alternative techniqueantibodies
Identity 19874
Gene BRD8
Long gene name bromodomain containing 8
Synonyms SMAP p120
Locus 5q31, 2
Discovery year 2003-02-07
GenBank acession AF016270
Entrez gene record 10902
Pubmed identfication 8611617 9368056
RefSeq identity NM_006696
Havana BLAST/BLAT OTTHUMG00000129204

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