Name : BRN3B Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN8453245340
| Long name | BRN3B Primary Polyclonal Antibody |
| Also known as | BRN3B PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | BRN3B |
| Specificity | This is a highly specific antibody against BRN3B |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human BRN3B/POU4F2 |
| Gene ID number | 5458 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Brn-1 and Brn-2 are class III POU (Pit-Oct-Unc) domain proteins, Brn-2 is thought to be involved in smooth muscle cell development and differentiation, Brn-3a has two functional transactivating domains, Brn-3b, Brn-3b and Brn-3c, Brn-3b generally functions as a transcriptional repressor, However, Interestingly, Three Brn-3 proteins have been described and are designated Brn-3a, While Brn-3a and Brn-3c stimulate transcription, but not Brn-3a, has been shown to regulate the expression of the acetylcholine receptor, one at the amino-terminus and one at the carboxy-terminus, whereas Brn-3 is a class IV POU domain protein, The Brn family of transcription factors are found in a highly restricted subset of neurons and are critical to the early embryonic development of the central nervous system |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | BRN3, Brain specic homeobox/POU domain protein 3B, Brain-3B, Brain-specic homeobox/POU domain protein 3B, Brn-3B, Brn3b POU domain transcription factor, PO4F2_HUMAN, POU class 4 homeobox 2, POU domain, POU domain class 4 transcription factor 2, POU domain protein, POU4F2, class 4, transcription factor 2, 2, BRN3B |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | BRN3B |
| Short name | BRN3B Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | BRN3B (Antibody to) |
| Alternative technique | antibodies |
| Identity | 9219 |
| Gene | POU4F2 |
| Long gene name | POU class 4 homeobox 2 |
| Synonyms gene | BRN3B |
| Synonyms gene name | POU domain, class 4, transcription factor 2 , transcription factor 2 POU domain class 4 |
| Synonyms | Brn-3b |
| Locus | 4q31, 22 |
| Discovery year | 1993-10-21 |
| GenBank acession | U06233 |
| Entrez gene record | 5458 |
| Pubmed identfication | 8332509 |
| RefSeq identity | NM_004575 |
| Classification | POU class homeoboxes and pseudogenes |
| Havana BLAST/BLAT | OTTHUMG00000162045 |