Name : c-Abl(Tyr276) Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :281
SKU : GEN1128060459
| Long name | c-Abl(Tyr276) Primary Polyclonal Antibody |
| Also known as | c-Abl(Tyr276) PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | c-AblTyr276 |
| Specificity | This is a highly specific antibody against c-AblTyr276 |
| Modification(s) | Phosphorylation |
| Modification site(s) | Tyr276 |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic phosphopeptide derived from human c-Abl isoform b around the phosphorylation site of Tyr276 |
| Gene ID number | 25 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | In chronic myelogenous leukemia and in a subset of acute lymphoblastic leukemias, The molecular consequence of this translocation is the generation of a chimeric Bcr/Abl mRNA encoding activated Abl protein tyrosine kinase, the c Abl proto oncogene undergoes a (9, 22) chromosomal translocation producing a novel rearranged chromosome (the Philadelphia chromosome) As the result of the fusion of c Abl sequences from chromosome 9 to the Bcr gene on chromosome 22, The c Abl proto oncogene encodes a protein tyrosine kinase that is located in the cytoplasm and nucleus |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | ABL, Abelson murine leukemia viral v abl oncogene homolog 1, Abl 1, Abl protein, Abl1, Bcr/c abl oncogene protein, JTK 7, JTK7, Proto oncogene tyrosine protein kinase ABL1, Transformation gene oncogene ABL, p150 , v abl, v abl Abelson murine leukemia viral oncogene homolog 1, Abelson Murine Leukemia Viral Oncogene Homolog 1 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | c-Abl(Tyr276) |
| Short name | c-Abl(Tyr276) Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | c-Abl(Tyr276) (Antibody to) |
| Alternative technique | antibodies |