Name : c-Ros Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN2102694953
| Long name | c-Ros Primary Polyclonal Antibody |
| Also known as | c-Ros PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | c-Ros |
| Specificity | This is a highly specific antibody against c-Ros |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 2300-2345/2347 |
| Subcellular location | Cytoplasm |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human c-Ros |
| Gene ID number | 6098 |
| Swiss Prot | P08922 |
| Tested Applications | IF(IHC-P), IHC-P |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | IRS1 and PLCG2, MAPK1, MAPK3, May activate other downstream signaling proteins including AKT1, May activate several downstream signaling pathways related to cell differentiation, May also phosphorylate and activate the transcription factor STAT3 to control anchorage-independent cell growth, Mediates the phosphorylation and the activation of VAV3, Mediates the phosphorylation of PTPN11, a guanine nucleotide exchange factor regulating cell morphology, an activator of this pathway, growth and survival including the PI3 kinase-mTOR signaling pathway, proliferation, Orphan receptor tyrosine kinase (RTK) that plays a role in epithelial cell differentiation and regionalization of the proximal epididymal epithelium |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | MCF3, Proto-oncogene c-Ros, Proto-oncogene c-Ros-1, Proto-oncogene tyrosine-protein kinase ROS, ROS1, Receptor tyrosine kinase c-ros oncogene 1, c-Ros receptor tyrosine kinase, c-ros-1, ROS |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | c-Ros |
| Short name | c-Ros Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | c-Ros (Antibody to) |
| Alternative technique | antibodies |
| Identity | 10261 |
| Gene | ROS1 |
| Long gene name | ROS proto-oncogene 1, receptor tyrosine kinase |
| Synonyms gene name | receptor tyrosine kinase , v-ros avian UR2 sarcoma virus oncogene homolog 1 v-ros UR2 sarcoma virus oncogene homolog 1 (avian) c-ros oncogene 1 |
| Synonyms | MCF3 ROS c-ros-1 |
| Locus | 6q22, 1 |
| Discovery year | 1986-01-01 |
| GenBank acession | M13599 |
| Entrez gene record | 6098 |
| Pubmed identfication | 1611909 |
| Classification | Fibronectin type III domain containing Receptor Tyrosine Kinases |
| Havana BLAST/BLAT | OTTHUMG00000016188 |
| Locus Specific Databases | LRG_997 |