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c-Src Antibody

c-Src Antibody size: 0.4 ml 406

Supplier NJS POLY
Price 406
Size 0.4 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormPurified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenc-Src
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, IF, WB, IHC
Recommended dilutionsIHC (Paraffin): 1:50-1:100, Immunofluorescence: 1:10-1:50, Western blot: 1:1000
NotesTitration of the c-Src antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis c-Src antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P12931
PurityPurified
Description It is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase, Mutations in Src could be involved in the malignant progression of colon cancer, This proto-oncogene may play a role in the regulation of embryonic development and cell growth, The gene for Src is highly similar to the v-src gene of Rous sarcoma virus
ImmunogenA portion of amino acids 1-30 from the human protein was used as the immunogen for this c-Src antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the c-Src antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetc-Src
Short namec-Src Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namec-v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) (Antibody to)
Alternative techniqueantibodies
Identity 2444
Gene CSK
Long gene name CSK, non-receptor tyrosine kinase
Synonyms gene name c-src tyrosine kinase
Locus 15q24, 1
Discovery year 1992-03-20
Entrez gene record 1445
Pubmed identfication 1377109
RefSeq identity NM_004383
Classification SH2 domain containing
Havana BLAST/BLAT OTTHUMG00000142814

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