Name : C14orf106 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN3344294582
| Long name | C14orf106 Primary Polyclonal Antibody |
| Also known as | C14orf106 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | C14orf106 |
| Specificity | This is a highly specific antibody against C14orf106 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human KNL2/C14orf106 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Chromosome 14 encodes the presinilin 1 (PSEN1) gene, It interacts with SP1, Notably, The C14orf106 gene product has been provisionally designated C14orf106 pending further characterization, The SERPINA1 gene is located on chromosome 14 and when defective leads to the genetic disorder ?-antitrypsin deficiency, There are two isoforms, This disorder is characterized by severe lung complications and liver dysfunction, the immunoglobulin heavy chain locus is found on chromosome 14 and has been identified as a fusion with the chromosome 19 encoded protein BCL3 in the (14, which is one of the three key genes associated with the development of Alzheimer's disease, 19) translocations found in a variety of B cell malignancies, 5% of human cellular DNA, C14orf106 is required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis, Chromosome 14 contains about 700 genes and 106 million base pairs and makes up about 3 |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | HsKNL-2, KIAA1903, Kinetochore-associated protein KNL-2 homolog, M18BP1, M18BP_HUMAN, MIS18BP1, Mis18-binding protein 1, P243, Putative protein p243 which interacts with transcription factor Sp1, Uncharacterized potential DNA binding protein C14orf106, Chromosome 14 open reading frame 106 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | C14orf106 |
| Short name | C14orf106 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | C14orf106 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 20190 |
| Gene | MIS18BP1 |
| Long gene name | MIS18 binding protein 1 |
| Synonyms gene | C14orf106 |
| Synonyms gene name | chromosome 14 open reading frame 106 |
| Synonyms | M18BP1 FLJ11186 KIAA1903 KNL2 |
| Synonyms name | elegans) , kinetochore null 2 homolog (C |
| Locus | 14q21, 2 |
| Discovery year | 2002-12-20 |
| GenBank acession | AB067490 |
| Entrez gene record | 55320 |
| Pubmed identfication | 17339379 17199038 |
| Classification | Myb/SANT domain containing |
| Havana BLAST/BLAT | OTTHUMG00000140266 |