Name : CARD4 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN5466376336
| Long name | CARD4 Primary Polyclonal Antibody |
| Also known as | CARD4 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | CARD4 |
| Specificity | This is a highly specific antibody against CARD4 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 64-105/953 |
| Subcellular location | Helical |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CARD4 |
| Gene ID number | 10392 |
| Swiss Prot | Q9Y239 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Confers responsiveness to intracellular bacterial lipopolysaccharides (LPS), Forms an intracellular sensing system along with ARHGEF2 for the detection of microbial effectors during cell invasion by pathogens, Induces NF-kappa-B activity via RIPK2 and IKK-gamma, Involved not only in sensing peptidoglycan (PGN)-derived muropeptides but also in the activation of NF-kappa-B by Shigella effector proteins IpgB2 and OspB, Recruits NLRP10 to the cell membrane following bacterial infection, Required for RHOA and RIPK2 dependent NF-kappa-B signaling pathway activation upon S, Enhances caspase-9-mediated apoptosis, flexneri cell invasion |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | CLR7, Caspase recruitment domain-containing protein 4, NLRC1, NOD1, Nucleotide-binding oligomerization domain-containing protein 1, 1, CARD4 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | CARD4 |
| Short name | CARD4 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | CARD4 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 16390 |
| Gene | NOD1 |
| Long gene name | nucleotide binding oligomerization domain containing 1 |
| Synonyms gene | CARD4 |
| Synonyms gene name | caspase recruitment domain family, member 4 |
| Synonyms | NLRC1 CLR7, 1 |
| Synonyms name | CARD domain containing 1 , leucine rich repeat and CARD domain containing 1 NLR family, nucleotide-binding oligomerization domain |
| Locus | 7p14, 3 |
| Discovery year | 2001-12-11 |
| GenBank acession | AF126484 |
| Entrez gene record | 10392 |
| Pubmed identfication | 10224040 10329646 |
| Classification | Caspase recruitment domain containing NLR family |
| Havana BLAST/BLAT | OTTHUMG00000023923 |