Name : CASC3(Tyr181) Antibody, ALEXA FLUOR 488
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :350
SKU : GEN2657880846
| Long name | ALEXA FLUOR 488 Conjugated, CASC3(Tyr181) Polyclonal Antibody |
| Also known as | Anti-CASC3 Tyr181 PAb ALEXA FLUOR 488 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 488, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | CASC3 Tyr181 |
| Specificity | This is a highly specific antibody against CASC3 Tyr181 |
| Modification | Phosphorylation |
| Modification Site | Tyr181 |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic phosphopeptide derived from human CASC3 around the phosphorylation site of Tyr181 |
| Gene ID Number | 22794 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Human MLN51 is an RNA-binding protein present in ribonucleo-protein complexes, In mammalian cells, Its fly homolog, MLN51 is a nucleocytoplasmic shuttling protein that is overexpressed in breast cancer, Magoh and Y14, The EJC is assembled on spliced mRNAs and plays important roles in post-splicing events including mRNA export, The function of MLN51 in mammals remains elusive, and translation, are core components of the exon junction complex (EJC), as well as the proteins mago nashi and tsunagi have been shown to be required for proper oskar mRNA localization to the posterior pole of the oocyte, named barentsz, nonsense-mediated mRNA decay, the human homologs of mago nashi and tsunagi, this complex serves as a key modulator of spliced mRNA metabolism, &euro, &ldquo, The multiprotein exon junction complex (EJC) is deposited on mRNAs upstream of exonâ, exon junctions as a consequence of pre-mRNA splicing |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 499nm/519nm |
| Synonyms | MLN51 BTZ |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the CASC3(Tyr181) Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Gene target | CASC3(Tyr181) |
| Short name | CASC3(Tyr181) Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 488 |
| Alternative name | ALEXA FLUOR 488, CASC3(Tyr181) (Antibody to) |
| Alternative technique | antibodies |
| Identity | 17040 |
| Gene | CASC3 |
| Long gene name | cancer susceptibility 3 |
| Synonyms gene name | cancer susceptibility candidate 3 |
| Locus | 17q21, 1 |
| Discovery year | 2004-02-11 |
| GenBank acession | X80199 |
| Entrez gene record | 22794 |
| Pubmed identfication | 7490069 18332872 |
| RefSeq identity | NM_007359 |
| Classification | Exon junction complex |
| Havana BLAST/BLAT | OTTHUMG00000133323 |